[HTML][HTML] A focus on yeast mating: From pheromone signaling to cell-cell fusion
Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …
CDK signaling via nonconventional CDK phosphorylation sites
Since the discovery of cyclin-dependent kinases (CDKs), it has been perceived as a dogma
that CDK signaling in the cell cycle is mediated via targeting the CDK consensus sites: the …
that CDK signaling in the cell cycle is mediated via targeting the CDK consensus sites: the …
[HTML][HTML] Who guards the guardian? Mechanisms that restrain APC/C during the cell cycle
J Kernan, T Bonacci, MJ Emanuele - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
The cell cycle is principally controlled by Cyclin Dependent Kinases (CDKs), whose
oscillating activities are determined by binding to Cyclin coactivators. Cyclins exhibit …
oscillating activities are determined by binding to Cyclin coactivators. Cyclins exhibit …
p38γ is essential for cell cycle progression and liver tumorigenesis
The cell cycle is a tightly regulated process that is controlled by the conserved cyclin-
dependent kinase (CDK)–cyclin protein complex. However, control of the G0-to-G1 transition …
dependent kinase (CDK)–cyclin protein complex. However, control of the G0-to-G1 transition …
Inflammatory cytokines as key players of apoptosis induced by environmental estrogens in the ovary
FL Zhang, L Kong, AH Zhao, W Ge, ZH Yan, L Li… - Environmental …, 2021 - Elsevier
Natural and synthetic environmental estrogens (EEs), interfering with the physiological
functions of the body's estrogens, are widespread and are rising much concern for their …
functions of the body's estrogens, are widespread and are rising much concern for their …
Fisetin decreases TET 1 activity and CCNY/CDK 16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell
Y Si, J Liu, H Shen, C Zhang, Y Wu… - Journal of cellular …, 2019 - Wiley Online Library
As a natural flavonol, fisetin has significant inhibitory effects on many cancers. Although
fisetin can inhibit kidney cancer, its effects on kidney renal stem cells (Hu RCSC s) remain …
fisetin can inhibit kidney cancer, its effects on kidney renal stem cells (Hu RCSC s) remain …
Hyperosmolality in CHO cell culture: effects on the proteome
N Romanova, L Schelletter, R Hoffrogge… - Applied microbiology and …, 2022 - Springer
Chinese hamster ovary (CHO) cells are the most commonly used host cell lines for
therapeutic protein production. Exposure of these cells to highly concentrated feed solution …
therapeutic protein production. Exposure of these cells to highly concentrated feed solution …
Comprehensive analysis of G1 cyclin docking motif sequences that control CDK regulatory potency in vivo
Many protein-modifying enzymes recognize their substrates via docking motifs, but the
range of functionally permissible motif sequences is often poorly defined. During eukaryotic …
range of functionally permissible motif sequences is often poorly defined. During eukaryotic …
Phosphorylation of plant microtubule-associated proteins during cell division
Progression of mitosis and cytokinesis depends on the reorganization of cytoskeleton, with
microtubules driving the segregation of chromosomes and their partitioning to two daughter …
microtubules driving the segregation of chromosomes and their partitioning to two daughter …
[HTML][HTML] The G1/S transition is promoted by Rb degradation via the E3 ligase UBR5
Mammalian cells make the decision to divide at the G1/S transition in response to diverse
signals impinging on the retinoblastoma protein Rb, a cell cycle inhibitor and tumor …
signals impinging on the retinoblastoma protein Rb, a cell cycle inhibitor and tumor …