Current developments of coumarin-based anti-cancer agents in medicinal chemistry

S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Synthetic and natural coumarins as cytotoxic agents

I Kostova - Current Medicinal Chemistry-Anti-Cancer Agents, 2005 - ingentaconnect.com
Coumarins, an old class of compounds, are naturally occurring benzopyrene derivatives. A
lot of coumarins have been identified from natural sources, especially green plants. The …

Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co (II), Ni (II) and Cu (II) complexes with 1, 2, 4-triazole Schiff bases

GB Bagihalli, PG Avaji, SA Patil, PS Badami - European journal of …, 2008 - Elsevier
A series of metal complexes of cobalt (II), nickel (II) and copper (II) have been synthesized
with newly synthesized biologically active 1, 2, 4-triazole Schiff bases derived from the …

Biological activity of metal ions complexes of chromones, coumarins and flavones

M Grazul, E Budzisz - Coordination chemistry reviews, 2009 - Elsevier
The medical properties of naturally occurring compounds such as chromones, flavonoids
and coumarins have been well known for many years. However, the discovery that their …

Metal complexes of flavonoids: Their synthesis, characterization and enhanced antioxidant and anticancer activities

M Khater, D Ravishankar, F Greco… - Future medicinal …, 2019 - Future Science
Flavonoids are polyphenolic compounds of natural origin. They are extensively studied
within drug discovery programs due to their wide ranging biological activities such as …

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver (I) complexes

BS Creaven, DA Egan, K Kavanagh, M McCann… - Inorganica Chimica …, 2006 - Elsevier
A series of new coumarin-derived carboxylate ligands and their silver (I) complexes have
been synthesized, characterized and screened for their in vitro antibacterial activity against a …

RETRACTED: In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based …

B Thati, A Noble, BS Creaven, M Walsh, M McCann… - 2007 - Elsevier
The chemotherapeutic potential of coumarin-3-carboxylic acid (C-3-COOH) and a series of
three hydroxylated coumarin-3-carboxylic acid ligands, namely 6-hydroxy-coumarin-3 …

Cytotoxic activity of new lanthanum (III) complexes of bis-coumarins

I Kostova, G Momekov, M Zaharieva… - European journal of …, 2005 - Elsevier
Complexes of lanthanum (III) with bis-coumarins: bis (4-hydroxy-2-oxo-2H-chromen-3-yl)-
piridin-2-yl-methane; bis (4-hydroxy-2-oxo-2H-chromen-3-yl)-piridin-3-yl-methane and bis (4 …

In vitro inhibition of intestinal motility by phenylethanolaminotetralines: evidence of atypical β‐adrenoceptors in rat colon

A Bianchetti, L Manara - British journal of pharmacology, 1990 - Wiley Online Library
1 The new compounds phenylethanolaminotetralines (PEAT), unlike the reference β‐
adrenoceptor agonists isoprenaline (Iso), ritodrine (Ri) and salbutamol (Sal), produced half …

Lanthanides as anticancer agents

I Kostova - Current Medicinal Chemistry-Anti-Cancer Agents, 2005 - ingentaconnect.com
The application of inorganic chemistry to medicine is a rapidly developing field, and novel
therapeutic and diagnostic metals and metal complexes are now having an impact on …