Transcriptome-wide mapping of milk somatic cells upon subclinical mastitis infection in dairy cattle

V Bisutti, N Mach, D Giannuzzi, A Vanzin… - Journal of Animal …, 2023 - Springer
Background Subclinical intramammary infection (IMI) represents a significant problem in
maintaining dairy cows' health. Disease severity and extent depend on the interaction …

Veterinary systems biology for bridging the phenotype–genotype gap via computational modeling for disease epidemiology and animal welfare

RK Pathak, JM Kim - Briefings in Bioinformatics, 2024 - academic.oup.com
Veterinary systems biology is an innovative approach that integrates biological data at the
molecular and cellular levels, allowing for a more extensive understanding of the …

[HTML][HTML] Application of Pan-Omics Technologies in Research on Important Economic Traits for Ruminants

Z Gao, Y Lu, M Li, Y Chong, J Hong, J Wu… - International Journal of …, 2024 - mdpi.com
The economic significance of ruminants in agriculture underscores the need for advanced
research methodologies to enhance their traits. This review aims to elucidate the …

Bta-miR-199a-3p inhibits LPS-induced inflammation in bovine mammary epithelial cells via the PI3K/AKT/NF-κB signaling pathway

Y Li, Q Ren, X Wang, Z Luoreng, D Wei - Cells, 2022 - mdpi.com
Mastitis is characterized by inflammatory damage to mammary gland tissue, which could
decline milk production and quality and significantly affect the economic benefits of …

Construction of a circRNA–lincRNA–lncRNA–miRNA–mRNA ceRNA regulatory network identifies genes and pathways linked to goat fertility

F Ghafouri, M Sadeghi, A Bahrami, M Naserkheil… - Frontiers in …, 2023 - frontiersin.org
Background: There is growing interest in the genetic improvement of fertility traits in female
goats. With high-throughput genotyping, single-cell RNA sequencing (scRNA-seq) is a …

Novel lncRNA regulatory elements in milk somatic cells of Holstein dairy cows associated with mastitis

V Asselstine, JF Medrano, MMM Muniz… - Communications …, 2024 - nature.com
Despite regulatory elements such as long non-coding RNAs representing most of the
transcriptome, the functional understanding of long non-coding RNAs in relation to major …

Multi-omics integration identifies regulatory factors underlying bovine subclinical mastitis

M Wang, N Yang, M Laterrière, D Gagné… - Journal of Animal …, 2024 - Springer
Background Mastitis caused by multiple factors remains one of the most common and costly
disease of the dairy industry. Multi-omics approaches enable the comprehensive …

Development and validation of a 5K low-density SNP chip for Hainan cattle

H Wang, H Wu, W Zhang, J Jiang, H Qian, C Man… - BMC genomics, 2024 - Springer
Background This study aimed to design and develop a 5K low-density liquid chip for Hainan
cattle utilizing targeted capture sequencing technology. The chip incorporates a substantial …

Integrated Analysis of Transcriptome Profiles and lncRNA–miRNA–mRNA Competing Endogenous RNA Regulatory Network to Identify Biological Functional Effects of …

F Ghafouri, V Dehghanian Reyhan, M Sadeghi… - Non-coding RNA, 2024 - mdpi.com
Paratuberculosis or Johne's disease (JD), a chronic granulomatous gastroenteritis caused
by Mycobacterium avium subsp. paratuberculosis (MAP), causes huge economic losses and …

Reliability of udder infrared thermography as a non-invasive technology for early detection of sub-clinical mastitis in Sahiwal (Bos indicus) cows under semi-intensive …

L Satheesan, PM Kittur, MN Alhussien, GS Lal… - Journal of Thermal …, 2024 - Elsevier
The present study focused on Sahiwal cows, a prominent milch breed in tropical India, to
correlate udder temperature with physiological markers of stress and inflammation during …