Axonal transport is essential for neuronal function, and many neurodevelopmental and
neurodegenerative diseases result from mutations in the axonal transport machinery …

The growth and migration of neurons require continuous remodelling of the neuronal
cytoskeleton, providing a versatile cellular framework for force generation and guided …

Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Despite the ability of peripheral nerves to spontaneously regenerate after injury, recovery is
generally very poor. The neurotrophins have emerged as an important modulator of axon …

Dendritic spines undergo actin-based growth and shrinkage during synaptic plasticity, in
which the actin depolymerizing factor (ADF)/cofilin family of actin-associated proteins are …

The axon is the single long fiber that extends from the neuron and transmits electrical
signals away from the cell body. The neuronal cytoskeleton, composed of microtubules …

Recent observations related to the structure of the cytoskeleton in neurons and novel
cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases …

Although actin at neuronal growth cones is well-studied, much less is known about actin
organization and dynamics along axon shafts and presynaptic boutons. Using probes that …

The corporeal beauty of the neuronal cytoskeleton has captured the imagination of
generations of scientists. One of the easiest cellular structures to visualize by light …

Neurites are the characteristic structural element of neurons that will initiate brain
connectivity and elaborate information. Early in development, neurons are spherical cells …