Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …

Gliomas represent the most common malignant primary brain tumors, and a high-grade
subset of these tumors including glioblastoma are particularly refractory to current standard …

Microglial cells are crucial in maintaining central nervous system (CNS) homeostasis and
mediating CNS disease pathogenesis. Increasing evidence supports that alterations in the …

Major obstacles in brain cancer treatment include the blood-tumor barrier (BTB), which limits
the access of most therapeutic agents, and quiescent tumor cells, which resist conventional …

In cell biology, fluorescent dyes are routinely used for biochemical measurements. The
traditional global dye treatment method suffers from low signal-to-noise ratios (SNR) …

Soft sensing is indispensable for precisely manipulate and recognize objects in soft robotics.
However, it is a challenge to better integrate soft robots with soft sensors because the …

Simple Summary Sonodynamic therapy (SDT) is a non-invasive technique that is based on
the combination of a sonosensitizer and acoustic activation that destroys the mitochondrial …

Brain tumors such as glioblastomas are resistant to immune checkpoint blockade therapy,
largely due to limited T cell infiltration in the tumors. Here, we show that mice bearing …

Glioblastoma is a highly aggressive brain tumor with a poor prognosis. Recent studies have
suggested that mechanobiology, the study of how physical forces influence cellular …

Dynamic observation of cell and tissue responses to elevated pressure could help our
understanding of important physiological and pathological processes related to pressure …