Health care and medicine were revolutionized in recent years by the development of
biomaterials, such as stents, implants, personalized drug delivery systems, engineered …

Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …

As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …

Tissue engineering (TE) is a promising approach for repairing diseased and damaged bone
tissue. Injectable hydrogel based strategies offer a wide range of applications in rapid …

Biopolymer coatings exhibit outstanding potential in various biomedical applications, due to
their flexible functionalization. In this review, we have discussed the latest developments in …

Background Differentiation of mesenchymal stem cells to osteoblasts is widely performed in
research laboratories. Classical tests to prove this differentiation employ procedures such as …

Concern regarding the reproducibility of observations in life science research has emerged
in recent years, particularly in view of unfavorable experiences with preclinical in vivo …

Hyaline cartilage plays a critical role in maintaining joint function and pain. However, the
lack of blood supply, nerves, and lymphatic vessels greatly limited the self-repair and …

Mesenchymal stem cell derived extracellular matrix (MSC-ECM) is a natural biomaterial with
robust bioactivity and good biocompatibility, and has been studied as a scaffold for tissue …