Oxidative stress, insulin signaling, and diabetes

JL Rains, SK Jain - Free radical biology and medicine, 2011 - Elsevier
Oxidative stress has been implicated as a contributor to both the onset and the progression
of diabetes and its associated complications. Some of the consequences of an oxidative …

[HTML][HTML] The role of oxidative stress and antioxidants in diabetic complications

FA Matough, SB Budin, ZA Hamid… - Sultan Qaboos …, 2012 - ncbi.nlm.nih.gov
Diabetes is considered to be one of the most common chronic diseases worldwide. There is
a growing scientific and public interest in connecting oxidative stress with a variety of …

A review on oxidative stress, diabetic complications, and the roles of honey polyphenols

VR Pasupuleti, CS Arigela, SH Gan… - Oxidative medicine …, 2020 - Wiley Online Library
Despite the availability of various antidiabetic drugs, diabetes mellitus (DM) remains one of
the world's most prevalent chronic diseases and is a global burden. Hyperglycaemia, a …

Pathological aspects of lipid peroxidation

A Negre-Salvayre, N Auge, V Ayala, H Basaga… - Free radical …, 2010 - Taylor & Francis
Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes

P Mohanty, W Hamouda, R Garg… - The journal of …, 2000 - academic.oup.com
Diabetes mellitus is associated with increased ROS generation, oxidative injury and obesity.
To elucidate the relationship between nutrition and ROS generation, we have investigated …

Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?

JL Styskal, H Van Remmen, A Richardson… - Free radical biology and …, 2012 - Elsevier
The development of metabolic dysfunctions like diabetes and insulin resistance in mammals
is regulated by a myriad of factors. Oxidative stress seems to play a central role in this …

Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome

F González, NS Rote, J Minium… - The Journal of Clinical …, 2006 - academic.oup.com
Context: Insulin resistance and chronic low level inflammation are often present in women
with polycystic ovary syndrome (PCOS). Objective: The purpose of this study was to …

Oxidative stress in autism: Increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin-the antioxidant proteins

A Chauhan, V Chauhan, WT Brown, I Cohen - Life sciences, 2004 - Elsevier
Autism is a neurological disorder of childhood with poorly understood etiology and
pathology. We compared lipid peroxidation status in the plasma of children with autism, and …

The role of oxidative stress in diabetic complications

DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer
The morbidity and mortality associated with diabetes is the result of the myriad complications
related to the disease. One of the most explored hypotheses to explain the onset of …

A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT‐6 secretion

LY Gao, S Guo, B McLaughlin, H Morisaki… - Molecular …, 2004 - Wiley Online Library
Initiation and maintenance of infection by mycobacteria in susceptible hosts are not well
understood. A screen of Mycobacterium marinum transposon mutant library led to isolation …