The hidden treasures in endophytic fungi: a comprehensive review on the diversity of fungal bioactive metabolites, usual analytical methodologies, and applications

JBA Dos Reis, AS Lorenzi, DB Pinho, PC Cortelo… - Archives of …, 2024 - Springer
This review provides a comprehensive overview of the key aspects of the natural metabolite
production by endophytic fungi, which has attracted significant attention due to its diverse …

Chlorinated Cyclopentene Derivatives and Antifungal Activities from Periconia sp. Induced by the One Strain Many Compounds Strategy and Host Plant Culture

YM Wu, XQ Yang, SY Li, JX Chen, T Wang… - Journal of Agricultural …, 2022 - ACS Publications
Eleven new chlorinated cyclopentene derivatives, periconsins AK, and a new
diketopiperazine, periconzin, were found from Periconia sp. cultured in three different media …

Uncovering Phytotoxic Compounds Produced by Colletotrichum spp. Involved in Legume Diseases Using an OSMAC–Metabolomics Approach

P Reveglia, FJ Agudo-Jurado, E Barilli, M Masi… - Journal of Fungi, 2023 - mdpi.com
Different fungal species belonging to the Colletotrichum genus cause anthracnose disease
in a range of major crops, resulting in huge economic losses worldwide. Typical symptoms …

Rapid Discovery of Substances with Anticancer Potential from Marine Fungi Based on a One Strain–Many Compounds Strategy and UPLC-QTOF-MS

YT Wu, XN Zhao, PX Zhang, CF Wang, J Li, XY Wei… - Marine Drugs, 2023 - mdpi.com
The secondary metabolites of marine fungi with rich chemical diversity and biological activity
are an important and exciting target for natural product research. This study aimed to …

OSMAC Method to Assess Impact of Culture Parameters on Metabolomic Diversity and Biological Activity of Marine-Derived Actinobacteria

A Le Loarer, L Dufossé, J Bignon, M Frédérich… - Marine drugs, 2023 - mdpi.com
Actinobacteria are known for their production of bioactive specialized metabolites, but they
are still under-exploited. This study uses the “One Strain Many Compounds”(OSMAC) …

Comparative Analysis of Secondary Metabolites Produced by Ascochyta fabae under In Vitro Conditions and Their Phytotoxicity on the Primary Host, Vicia faba, and …

E Barilli, P Reveglia, FJ Agudo-Jurado… - Toxins, 2023 - mdpi.com
Ascochyta blight, caused by Ascochyta fabae, poses a significant threat to faba bean and
other legumes worldwide. Necrotic lesions on stems, leaves, and pods characterize the …

New piperazine derivatives helvamides B–C from the marine-derived fungus Penicillium velutinum ZK-14 uncovered by OSMAC (One Strain Many Compounds) …

GV Borkunov, EV Leshchenko, DV Berdyshev… - Natural Products and …, 2024 - Springer
Four extracts of the marine-derived fungus Penicillium velutinum JFH Beyma were obtained
via metal ions stress conditions based on the OSMAC (One Strain Many Compounds) …