Febrile seizures are one of the commonest presentations in young children, with a 2–5%
incidence in Western countries. Though they are generally benign, with rare long-term …

During the last decade, experimental research has demonstrated a prominent role of glial
cells, activated in brain by various injuries, in the mechanisms of seizure precipitation and …

Background Herpes simplex encephalitis can trigger autoimmune encephalitis that leads to
neurological worsening. We aimed to assess the frequency, symptoms, risk factors, and …

Although seizures are frequent in all types of autoimmune encephalitis, the risk for chronic
epilepsy is dependent on the antigen: lower if located on the cell-surface, and higher if …

Febrile seizure (FS) is the most common seizure disorder of childhood, and occurs in an age-
related manner. FS are classified into simple and complex. FS has a multifactorial …

Genetic mutations causing dysfunction of both voltage‐and ligand‐gated ion channels make
a major contribution to the cause of many different types of familial epilepsy. Key …

CME Educational Objectives 1. Discuss the classification, epidemiology, and
pathophysiology of febrile seizures in children. 2. Review the evaluation, management, and …

Animal models contribute greatly to our understanding of brain development and function as
well as its dysfunction in neurological diseases. Epilepsy research is a very good example of …

Background Health professionals frequently recommend fever treatment regimens for
children that either combine paracetamol and ibuprofen or alternate them. However, there is …

The liver secretory protein fetuin-A (FetA) is now shown to act as an adaptor protein between
free fatty acids (FFAs) and Toll-like receptor 4 (TLR4), providing the missing link between …