The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Cardiovascular disease is the leading cause of death in women and men globally, with most
due to atherosclerotic cardiovascular disease (ASCVD). Despite progress during the last 30 …

This expert consensus statement summarizes the available data regarding the prognostic
value of CAC in the asymptomatic population and its ability to refine individual risk …

Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …

Coronary artery calcium scanning (CAC) has emerged as the most robust predictor of
coronary events in the asymptomatic primary prevention population, particularly in the …

Infection and inflammation induce the acutephase response (APR), leading to multiple
alterations in lipid and lipoprotein metabolism. Plasma triglyceride levels increase from …

Angiogenesis is a hallmark of malignant neoplasias, as the formation of new blood vessels
is required for tumors to acquire oxygen and nutrients essential for their continued growth …

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …

Background Although systemic lupus erythematosus is associated with premature
myocardial infarction, the prevalence of underlying atherosclerosis and its relation to …