Studying non-covalent drug–DNA interactions
Drug–DNA interactions have been extensively studied in the recent past. Various
techniques have been employed to decipher these interactions. DNA is a major target for a …
techniques have been employed to decipher these interactions. DNA is a major target for a …
Intrinsically fluorescent anti-cancer drugs
Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …
development of anti-cancer drugs is important in combatting this disease. As good as these …
A novel view of the separate and simultaneous binding effects of docetaxel and anastrozole with calf thymus DNA: Experimental and in silico approaches
M Dareini, ZA Tehranizadeh, N Marjani… - … Acta Part A: Molecular …, 2020 - Elsevier
DNA stands as the primary purpose of many anticancer drugs and according to the
performed research on this field, some certain changes contain crucial functionalities in the …
performed research on this field, some certain changes contain crucial functionalities in the …
Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies
Binding of toxic ligands to DNA could result in undesirable biological processes, such as
carcinogenesis or mutagenesis. Binding mode of Abiraterone (ABR), a steroid drug and calf …
carcinogenesis or mutagenesis. Binding mode of Abiraterone (ABR), a steroid drug and calf …
Binding interaction between sorafenib and calf thymus DNA: spectroscopic methodology, viscosity measurement and molecular docking
JH Shi, J Chen, J Wang, YY Zhu - … Acta Part A: Molecular and Biomolecular …, 2015 - Elsevier
The binding interaction of sorafenib with calf thymus DNA (ct-DNA) was studied using UV–
vis absorption spectroscopy, fluorescence emission spectroscopy, circular dichroism (CD) …
vis absorption spectroscopy, fluorescence emission spectroscopy, circular dichroism (CD) …
Antioxidant, antimicrobial and cytotoxic activities of silver and gold nanoparticles synthesized using Plumbago zeylanica bark
Utilization of bioresources for the synthesis of metal nanoparticles is the latest field in green
chemistry. The present work reports the utilization of the aqueous bark extract of Plumbago …
chemistry. The present work reports the utilization of the aqueous bark extract of Plumbago …
[HTML][HTML] Characterization of interaction of calf thymus DNA with gefitinib: Spectroscopic methods and molecular docking
JH Shi, TT Liu, M Jiang, J Chen, Q Wang - Journal of Photochemistry and …, 2015 - Elsevier
The binding interaction of gefitinib with calf thymus DNA (ct-DNA) under the simulated
physiological pH condition was studied employing UV absorption, fluorescence, circular …
physiological pH condition was studied employing UV absorption, fluorescence, circular …
Binding characteristics of sodium saccharin with calf thymus DNA in vitro
G Zhang, L Wang, X Zhou, Y Li… - Journal of Agricultural and …, 2014 - ACS Publications
The binding characteristics of sodium saccharin (SSA), an artificial sweetener, with calf
thymus DNA (ctDNA) were investigated by multispectroscopic techniques, chemometrics …
thymus DNA (ctDNA) were investigated by multispectroscopic techniques, chemometrics …
Deciphering the DNA-binding affinity, cytotoxicity and apoptosis induce as the anticancer mechanism of Bavachinin: An experimental and computational investigation
MF Dehkordi, S Farhadian, M Abdolvand… - Journal of Molecular …, 2021 - Elsevier
One of the most important mechanism by which bioflavonoids can exert their effects in
cancer treatment, is through their interaction with bio-macromolecules such as DNA. Recent …
cancer treatment, is through their interaction with bio-macromolecules such as DNA. Recent …
[HTML][HTML] Study on the interaction of the drug mesalamine with calf thymus DNA using molecular docking and spectroscopic techniques
N Shahabadi, SM Fili, F Kheirdoosh - Journal of Photochemistry and …, 2013 - Elsevier
The interaction of CT-DNA with the drug mesalamine (5-ASA) at physiological pH has been
investigated by absorption, emission, circular dichroism (CD), cyclic voltammetry (CV) …
investigated by absorption, emission, circular dichroism (CD), cyclic voltammetry (CV) …