Studying non-covalent drug–DNA interactions

SU Rehman, T Sarwar, MA Husain, HM Ishqi… - Archives of biochemistry …, 2015 - Elsevier
Drug–DNA interactions have been extensively studied in the recent past. Various
techniques have been employed to decipher these interactions. DNA is a major target for a …

Intrinsically fluorescent anti-cancer drugs

ML Kabir, F Wang, AHA Clayton - Biology, 2022 - mdpi.com
Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …

A novel view of the separate and simultaneous binding effects of docetaxel and anastrozole with calf thymus DNA: Experimental and in silico approaches

M Dareini, ZA Tehranizadeh, N Marjani… - … Acta Part A: Molecular …, 2020 - Elsevier
DNA stands as the primary purpose of many anticancer drugs and according to the
performed research on this field, some certain changes contain crucial functionalities in the …

Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies

TA Wani, N Alsaif, AH Bakheit, S Zargar… - Bioorganic …, 2020 - Elsevier
Binding of toxic ligands to DNA could result in undesirable biological processes, such as
carcinogenesis or mutagenesis. Binding mode of Abiraterone (ABR), a steroid drug and calf …

Binding interaction between sorafenib and calf thymus DNA: spectroscopic methodology, viscosity measurement and molecular docking

JH Shi, J Chen, J Wang, YY Zhu - … Acta Part A: Molecular and Biomolecular …, 2015 - Elsevier
The binding interaction of sorafenib with calf thymus DNA (ct-DNA) was studied using UV–
vis absorption spectroscopy, fluorescence emission spectroscopy, circular dichroism (CD) …

Antioxidant, antimicrobial and cytotoxic activities of silver and gold nanoparticles synthesized using Plumbago zeylanica bark

S Priya Velammal, TA Devi, TP Amaladhas - Journal of Nanostructure in …, 2016 - Springer
Utilization of bioresources for the synthesis of metal nanoparticles is the latest field in green
chemistry. The present work reports the utilization of the aqueous bark extract of Plumbago …

[HTML][HTML] Characterization of interaction of calf thymus DNA with gefitinib: Spectroscopic methods and molecular docking

JH Shi, TT Liu, M Jiang, J Chen, Q Wang - Journal of Photochemistry and …, 2015 - Elsevier
The binding interaction of gefitinib with calf thymus DNA (ct-DNA) under the simulated
physiological pH condition was studied employing UV absorption, fluorescence, circular …

Binding characteristics of sodium saccharin with calf thymus DNA in vitro

G Zhang, L Wang, X Zhou, Y Li… - Journal of Agricultural and …, 2014 - ACS Publications
The binding characteristics of sodium saccharin (SSA), an artificial sweetener, with calf
thymus DNA (ctDNA) were investigated by multispectroscopic techniques, chemometrics …

Deciphering the DNA-binding affinity, cytotoxicity and apoptosis induce as the anticancer mechanism of Bavachinin: An experimental and computational investigation

MF Dehkordi, S Farhadian, M Abdolvand… - Journal of Molecular …, 2021 - Elsevier
One of the most important mechanism by which bioflavonoids can exert their effects in
cancer treatment, is through their interaction with bio-macromolecules such as DNA. Recent …

[HTML][HTML] Study on the interaction of the drug mesalamine with calf thymus DNA using molecular docking and spectroscopic techniques

N Shahabadi, SM Fili, F Kheirdoosh - Journal of Photochemistry and …, 2013 - Elsevier
The interaction of CT-DNA with the drug mesalamine (5-ASA) at physiological pH has been
investigated by absorption, emission, circular dichroism (CD), cyclic voltammetry (CV) …