The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
[HTML][HTML] Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: a consensus statement by the Society for …
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations
in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR) …
in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR) …
Addressing fairness in artificial intelligence for medical imaging
A plethora of work has shown that AI systems can systematically and unfairly be biased
against certain populations in multiple scenarios. The field of medical imaging, where AI …
against certain populations in multiple scenarios. The field of medical imaging, where AI …
Non-linear Mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk
A Zhou, JB Selvanayagam… - European heart …, 2022 - academic.oup.com
Aims Low vitamin D status is associated with a higher risk for cardiovascular diseases
(CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null …
(CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null …
Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity
AR Harper, A Goel, C Grace, KL Thomson… - Nature …, 2021 - nature.com
Hypertrophic cardiomyopathy (HCM) is a common, serious, genetic heart disorder. Rare
pathogenic variants in sarcomere genes cause HCM, but with unexplained phenotypic …
pathogenic variants in sarcomere genes cause HCM, but with unexplained phenotypic …
Deep learning techniques for automatic MRI cardiac multi-structures segmentation and diagnosis: is the problem solved?
Delineation of the left ventricular cavity, myocardium, and right ventricle from cardiac
magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish …
magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish …
Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect
The heart muscle diseases hypertrophic (HCM) and dilated (DCM) cardiomyopathies are
leading causes of sudden death and heart failure in young, otherwise healthy, individuals …
leading causes of sudden death and heart failure in young, otherwise healthy, individuals …
[HTML][HTML] Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
Background Cardiovascular resonance (CMR) imaging is a standard imaging modality for
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …
Anatomically constrained neural networks (ACNNs): application to cardiac image enhancement and segmentation
Incorporation of prior knowledge about organ shape and location is key to improve
performance of image analysis approaches. In particular, priors can be useful in cases …
performance of image analysis approaches. In particular, priors can be useful in cases …