Recent advances in enantioselective Pd-catalyzed allylic substitution: from design to applications
O Pamies, J Margalef, S Canellas, J James… - Chemical …, 2021 - ACS Publications
This Review compiles the evolution, mechanistic understanding, and more recent advances
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …
Stereoselective synthesis and applications of spirocyclic oxindoles
AJ Boddy, JA Bull - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …
stereoselective manner is an ongoing significant objective in organic and medicinal …
Further developments and applications of oxazoline-containing ligands in asymmetric catalysis
The chiral oxazoline motif is present in many ligands that have been extensively applied in a
series of important metal-catalyzed enantioselective reactions. This Review aims to provide …
series of important metal-catalyzed enantioselective reactions. This Review aims to provide …
Pd-Catalysed asymmetric allylic alkylation of heterocycles: a user's guide
F Richard, P Clark, A Hannam, T Keenan… - Chemical Society …, 2024 - pubs.rsc.org
This review provides an in-depth analysis of recent advances and strategies employed in
the Pd-catalysed asymmetric allylic alkylation (Pd-AAA) of nucleophilic prochiral …
the Pd-catalysed asymmetric allylic alkylation (Pd-AAA) of nucleophilic prochiral …
Catalytic enantioselective and diastereoselective allylic alkylation with fluoroenolates: efficient access to C3‐fluorinated and all‐carbon quaternary oxindoles
K Balaraman, C Wolf - Angewandte Chemie International …, 2017 - Wiley Online Library
Abstract Synthetically versatile 3, 3‐disubstituted fluorooxindoles exhibiting vicinal chirality
centers were obtained in high yields and with excellent enantio‐, diastereo‐, and …
centers were obtained in high yields and with excellent enantio‐, diastereo‐, and …
Enantioselective Synthesis of Dihydrospiro[indoline-3,4′-pyrano[2,3-c]pyrazole] Derivatives via Michael/Hemiketalization Reaction
N Kumarswamyreddy, V Kesavan - Organic letters, 2016 - ACS Publications
A new bifunctional squaramide organocatalyst derived from l-proline mediated the first
enantioselective synthesis of dihydrospiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole] …
enantioselective synthesis of dihydrospiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole] …
Stereodivergent Pd/Cu catalysis: asymmetric alkylation of racemic symmetrical 1, 3-diphenyl allyl acetates
We report a stereodivergent Pd/Cu catalyst system that was successfully applied to the
asymmetric allylic alkylation of symmetrical 1, 3-disubstituted allyl acetates with prochiral …
asymmetric allylic alkylation of symmetrical 1, 3-disubstituted allyl acetates with prochiral …
Enantioselective synthesis of 3, 3-disubstituted oxindoles bearing two different heteroatoms at the C3 position by organocatalyzed sulfenylation and selenenylation of …
Y You, ZJ Wu, ZH Wang, XY Xu… - The Journal of …, 2015 - ACS Publications
Catalytic asymmetric sulfenylation and selenenylation of 3-pyrrolyl-oxindoles for the
synthesis of 3, 3-disubstituted oxindoles bearing two different heteroatoms at the C3 position …
synthesis of 3, 3-disubstituted oxindoles bearing two different heteroatoms at the C3 position …
[HTML][HTML] Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update
B Yu, H Xing, DQ Yu, HM Liu - Beilstein Journal of Organic …, 2016 - beilstein-journals.org
Oxindole scaffolds are prevalent in natural products and have been recognized as
privileged substructures in new drug discovery. Several oxindole-containing compounds …
privileged substructures in new drug discovery. Several oxindole-containing compounds …
Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds
Several oxindole derivatives, of natural or synthetic origin, have been identified as
medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy …
medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy …