Non-healing wound is a serious complication of diabetes, associated with extremely slow
wound closure, and a high rate of infection, resulting in amputation or losses of limbs, high …

Type 2 diabetes is associated with several potential comorbidities, among them impaired
wound healing, chronic ulcerations, and the requirement for lower extremity amputation …

The treatment of diabetic wounds (DWs) is always challenging for the medical community
because of its multifaceted pathophysiology. Due to practical and ethical considerations …

ABSTRACT A growing body of evidence suggests that in addition to hypoxia, ischemia‐
reperfusion injury, and intrinsic host factors, bacterial biofilms represent a fourth major pillar …

There is a critical clinical need to develop therapies for nonhealing diabetic foot ulcers.
Topically applied mesenchymal stromal cells (MSCs) provide a novel treatment to augment …

This study was to create a long‐term rabbit model of diabetes mellitus for medical studies of
up to one year or longer and to evaluate the effects of chronic hyperglycemia on damage of …

Fibrin sealants, that have been employed for over a century by surgeons to stop post surgery
bleeding, are finding novel applications in the controlled delivery of antibiotics and several …

Functionalisation of biomaterials with therapeutic moieties (proteins, drugs, genes) is a pre-
requisite to tissue regeneration and restoration of function following injury or disease …

Diabetes mellitus and periodontitis are chronic inflammatory diseases that disrupt soft tissue
metabolism. The diseases separately or together increase apoptosis in gingival fibroblast …

Introduction Diabetic foot ulceration is the leading cause of amputation in people with
diabetes mellitus. Peripheral vascular disease is present in the majority of patients with …