Mosquito innate immunity

A Kumar, P Srivastava, P Sirisena, SK Dubey, R Kumar… - Insects, 2018 - mdpi.com
Mosquitoes live under the endless threat of infections from different kinds of pathogens such
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …

A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies

ST Ogunlade, MT Meehan, AI Adekunle, DP Rojas… - Vaccines, 2021 - mdpi.com
Arthropod-borne viruses (Arboviruses) continue to generate significant health and economic
burdens for people living in endemic regions. Of these viruses, some of the most important …

Temperature drives Zika virus transmission: evidence from empirical and mathematical models

B Tesla, LR Demakovsky… - … of the Royal …, 2018 - royalsocietypublishing.org
Temperature is a strong driver of vector-borne disease transmission. Yet, for emerging
arboviruses we lack fundamental knowledge on the relationship between transmission and …

Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids

YP Xu, Y Qiu, B Zhang, G Chen, Q Chen, M Wang… - Cell research, 2019 - nature.com
The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global
public health crisis since 2015. ZIKV preferentially infects and targets human neural …

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection

WS Lee, JA Webster, ET Madzokere, EB Stephenson… - Parasites & vectors, 2019 - Springer
Mosquito-borne diseases are associated with major global health burdens. Aedes spp. and
Culex spp. are primarily responsible for the transmission of the most medically important …

Flavivirus induces and antagonizes antiviral RNA interference in both mammals and mosquitoes

Y Qiu, YP Xu, M Wang, M Miao, H Zhou, J Xu… - Science …, 2020 - science.org
Mosquito-borne flaviviruses infect both mammals and mosquitoes. RNA interference (RNAi)
has been demonstrated as an anti-flavivirus mechanism in mosquitoes; however, whether …

Vector specificity of arbovirus transmission

M Viglietta, R Bellone, AA Blisnick… - Frontiers in …, 2021 - frontiersin.org
More than 25% of human infectious diseases are vector-borne diseases (VBDs). These
diseases, caused by pathogens shared between animals and humans, are a growing threat …

The Zika virus capsid disrupts corticogenesis by suppressing dicer activity and miRNA biogenesis

J Zeng, S Dong, Z Luo, X Xie, B Fu, P Li, C Liu, X Yang… - Cell Stem Cell, 2020 - cell.com
Zika virus (ZIKV) causes microcephaly and disrupts neurogenesis. Dicer-mediated miRNA
biogenesis is required for embryonic brain development and has been suggested to be …

Pathophysiology and mechanisms of Zika virus infection in the nervous system

KM Christian, H Song, G Ming - Annual review of neuroscience, 2019 - annualreviews.org
In 2015, public awareness of Zika virus (ZIKV) rose in response to alarming statistics of
infants with microcephaly being born to women who were infected with the virus during …

Mosquito antiviral immune pathways

CV Tikhe, G Dimopoulos - Developmental & Comparative Immunology, 2021 - Elsevier
Mosquitoes are vectors of a large number of viral pathogens. In recent years, increased
urbanization and climate change has expanded the range of many vector mosquitoes. The …