[HTML][HTML] Matrix metalloproteinases participation in the metastatic process and their diagnostic and therapeutic applications in cancer
G Gonzalez-Avila, B Sommer… - Critical reviews in …, 2019 - Elsevier
Matrix metalloproteinases (MMPs) participate from the initial phases of cancer onset to the
settlement of a metastatic niche in a second organ. Their role in cancer progression is …
settlement of a metastatic niche in a second organ. Their role in cancer progression is …
Matrix metalloproteinases in normal pregnancy and preeclampsia
J Chen, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …
Passing the baton: the HIF switch
MY Koh, G Powis - Trends in biochemical sciences, 2012 - cell.com
Hypoxia is an inadequate oxygen supply to tissues and cells, which can restrict their
function. The hypoxic response is primarily mediated by the hypoxia-inducible transcription …
function. The hypoxic response is primarily mediated by the hypoxia-inducible transcription …
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
GA Rosenberg - The Lancet Neurology, 2009 - thelancet.com
Matrix metalloproteinases (MMPs) and proteins containing a disintegrin and
metalloproteinase domain (ADAM) are important in neuroinflammation, and recent studies …
metalloproteinase domain (ADAM) are important in neuroinflammation, and recent studies …
'Go or grow': the key to the emergence of invasion in tumour progression?
H Hatzikirou, D Basanta, M Simon… - … and biology: a …, 2012 - academic.oup.com
Uncontrolled proliferation and abnormal cell migration are two of the main characteristics of
tumour growth. Of ultimate importance is the question what are the mechanisms that trigger …
tumour growth. Of ultimate importance is the question what are the mechanisms that trigger …
Glioblastoma microenvironment and invasiveness: new insights and therapeutic targets
Glioblastoma (GBM) is the most common and malignant primary brain cancer in adults.
Without treatment the mean patient survival is approximately 6 months, which can be …
Without treatment the mean patient survival is approximately 6 months, which can be …
The role of hypoxia inducible factor‐1 in hepatocellular carcinoma
D Luo, Z Wang, J Wu, C Jiang… - BioMed research …, 2014 - Wiley Online Library
Hypoxia is a common feature of many solid tumors, including hepatocellular carcinoma
(HCC). Hypoxia can promote tumor progression and induce radiation and chemotherapy …
(HCC). Hypoxia can promote tumor progression and induce radiation and chemotherapy …
Matrix metalloproteinases' role in tumor microenvironment
G Gonzalez-Avila, B Sommer… - … Matrix Components–Part …, 2020 - Springer
Cancer cells evolve in the tumor microenvironment (TME) by the acquisition of
characteristics that allow them to initiate their passage through a series of events that …
characteristics that allow them to initiate their passage through a series of events that …
Hypoxia-inducible factors as molecular targets for liver diseases
C Ju, SP Colgan, HK Eltzschig - Journal of molecular medicine, 2016 - Springer
Liver disease is a growing global health problem, as deaths from end-stage liver cirrhosis
and cancer are rising across the world. At present, pharmacologic approaches to effectively …
and cancer are rising across the world. At present, pharmacologic approaches to effectively …
Tumor metabolism, the ketogenic diet and β-hydroxybutyrate: novel approaches to adjuvant brain tumor therapy
EC Woolf, N Syed, AC Scheck - Frontiers in molecular neuroscience, 2016 - frontiersin.org
Malignant brain tumors are devastating despite aggressive treatments such as surgical
resection, chemotherapy and radiation therapy. The average life expectancy of patients with …
resection, chemotherapy and radiation therapy. The average life expectancy of patients with …