Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions

SP Rendić, RD Crouch, FP Guengerich - Archives of Toxicology, 2022 - Springer
This is an overview of the metabolic reactions of drugs, natural products, physiological
compounds, and other (general) chemicals catalyzed by flavin monooxygenase (FMO) …

Chiral separation and determination of R/S-methamphetamine and its metabolite R/S-amphetamine in urine using LC–MS/MS

T Wang, B Shen, Y Shi, P Xiang, Z Yu - Forensic Science International, 2015 - Elsevier
Methamphetamine (MA) and amphetamine (AM) are widely abused drugs. Differentiation of
MA and/or AM abuse from therapeutic ingestion of MA and/or AM or one of their precursor …

[PDF][PDF] Drugs in hair. Part I. Metabolisms of major drug classes

RM White - Forensic Sci Rev, 2017 - forensicsciencereview.com
Currently, hair can be reliably tested for the presence of drugs. However, one major
drawback to the use of parent drugs is the question of potential external or environmental …

Patterns of drugs and drug metabolites observed in meconium: what do they mean?

GA McMillin, KE Wood, FG Strathmann… - Therapeutic Drug …, 2015 - journals.lww.com
Background: Meconium drug testing is performed to detect potentially harmful drug
exposures in a newborn. Interpretation of meconium drug testing results can be complicated …

Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: preliminary findings

M Cherner, C Bousman, I Everall, D Barron… - Journal of the …, 2010 - cambridge.org
While neuropsychological deficits are evident among methamphetamine (meth) addicts,
they are often unrelated to meth exposure parameters such as lifetime consumption and …

Orthogonal array optimization of microwave-assisted derivatization for determination of trace amphetamine and methamphetamine using negative chemical ionization …

LW Chung, KL Lin, TCC Yang, MR Lee - Journal of Chromatography A, 2009 - Elsevier
An orthogonal array design (OAD) was applied to optimize microwave-assisted
derivatization (MAD) for analysis of trace amphetamine (AM) and methamphetamine (MA) by …

CYP2D6 genotype may moderate measures of brain structure in methamphetamine users

AC Dean, EL Nurmi, AM Morales, AK Cho… - Addiction …, 2021 - Wiley Online Library
Chronic methamphetamine use is linked to abnormalities in brain structure, which may
reflect neurotoxicity related to metabolism of the drug. As the cytochrome P450 2D6 …

Dispersive solid-phase extraction for simultaneous determination of four amphetamines drugs in urine using gas chromatography–mass spectrometry

MZ Elboraie, AA Elbashir, EEM Eid… - Journal of the Iranian …, 2022 - Springer
A sample preparation method based on modified Quick, Easy, Cheap Effective, Rugged,
and Safe (QuEChERS) and GC–MS method was developed and validated for identification …

[HTML][HTML] Analysis of amphetaminic drug compounds in urine by headspace-dielectric barrier discharge ionization-mass spectrometry

A Habib, A Nargis, L Bi, P Zhao, L Wen - Arabian Journal of Chemistry, 2020 - Elsevier
Rapid detection of trace level amphetaminic drug compounds in urine is essential to monitor
consumption of these abuse drugs by athletes. In this work, the amphetaminic drug …

Enantiomeric profile of amphetamines in seized drug samples and in blood of impaired drivers in Iceland: the rise of (R)-methamphetamine?

AE Bauer, MR Jakobsdottir… - Journal of Analytical …, 2024 - academic.oup.com
Amphetamine (AMP) and methamphetamine (METH) use is increasing globally. Illegal AMP
is generally a racemic mixture, whereas AMP-containing attention-deficit hyperactivity …