In vertebrates, multiciliated cells (MCCs) are terminally differentiated cells that line the
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …

Mechanosensing is a ubiquitous process to translate external mechanical stimuli into
biological responses. Piezo1 ion channels are directly gated by mechanical forces and play …

The generation of efficient fluid flow is crucial for organismal development and homeostasis,
sexual reproduction, and motility. Multi‐ciliated cells possess fields of motile cilia that beat in …

Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along
various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to …

Multiciliated cells (MCCs) are terminally differentiated epithelia that assemble multiple motile
cilia used to promote fluid flow. To template these cilia, MCCs dramatically expand their …

Motile cilia on the cell surface generate movement and directional fluid flow that is crucial for
various biological processes. Dysfunction of these cilia causes human diseases such as …

During embryogenesis, tissues develop into elaborate collectives through a myriad of active
mechanisms, with cell migration being one of the most common. As cells migrate, they …

Multiciliated cells (MCC) are evolutionary conserved, highly specialized cell types that
contain dozens to hundreds of motile cilia that they use to propel fluid directionally. To …

Xenopus embryos are covered with a complex epithelium containing numerous multiciliated
cells (MCCs). During late-stage development, there is a dramatic remodeling of the …

The epithelial adaptations to mechanical stress are facilitated by molecular and tissue-scale
changes that include the strengthening of junctions, cytoskeletal reorganization, and cell …