Connecting the dots: The boons and banes of network modeling

S Climer - Patterns, 2021 - cell.com
Network modeling transforms data into a structure of nodes and edges such that edges
represent relationships between pairs of objects, then extracts clusters of densely connected …

Climatic clustering and longitudinal analysis with impacts on food, bioenergy, and pandemics

J Lagergren, M Cashman, VGM Vergara… - Phytobiomes …, 2023 - Am Phytopath Society
Predicted growth in world population will put unparalleled stress on the need for sustainable
energy and global food production, as well as increase the likelihood of future pandemics. In …

Longitudinal effects on plant species involved in agriculture and pandemic emergence undergoing changes in abiotic stress

M Cashman, V G. Melesse Vergara… - Proceedings of the …, 2023 - dl.acm.org
In this work we identify changes in high-resolution zones across the globe linked by
environmental similarity that have implications for agriculture, bioenergy, and zoonosis. We …

Data-Driven Whole-Genome Clustering to Detect Geospatial, Temporal, and Functional Trends in SARS-CoV-2 Evolution

J Merlet, J Lagergren, V Melesse Vergara… - Proceedings of the …, 2023 - dl.acm.org
Current methods for defining SARS-CoV-2 lineages ignore the vast majority of the SARS-
CoV-2 genome. We develop and apply an exhaustive vector comparison method that …

Heterogeneity impacts biomarker discovery for precision medicine

K Smith, S Climer - medRxiv, 2022 - medrxiv.org
Precision medicine is advancing patient care for complex human diseases. Discovery of
biomarkers to diagnose specific subtypes within a heterogeneous diseased population is a …

Mr. Clean: An Ensemble of Data Cleaning Algorithms for Increased Data Retention

K Smith, S Climer - 2023 IEEE International Conference on …, 2023 - ieeexplore.ieee.org
Handling missing data is a critical issue in nearly all analytical fields. Techniques that
address this problem are generally categorized as either imputation or deletion algorithms …

A search and filter strategy for identifying differentially co-expressed analyte modules

J Lea, S Climer - 2020 IEEE International Conference on …, 2020 - ieeexplore.ieee.org
Biological pathways underlying complex traits of interest are comprised of numerous
analytes working in concert to produce the phenotype. Correlation network analysis (CNA) is …

Data-Driven Whole-Genome Clustering to Detect Geospatial, Temporal, and Functional Trends in SARS-CoV-2 Evolution

D Jacobson, J Lagergren, W Joubert, C Bradburne… - 2023 - osti.gov
Current methods for defining SARS-CoV-2 lineages ignore the vast majority of the SARS-
CoV-2 genome. We develop and apply an exhaustive vector comparison method that …