High cholesterol/low cholesterol: effects in biological membranes: a review

WK Subczynski, M Pasenkiewicz-Gierula… - Cell biochemistry and …, 2017 - Springer
Lipid composition determines membrane properties, and cholesterol plays a major role in
this determination as it regulates membrane fluidity and permeability, as well as induces the …

Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?

T Róg, I Vattulainen - Chemistry and physics of lipids, 2014 - Elsevier
Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

Membrane models and experiments suitable for studies of the cholesterol bilayer domains

I Mardešić, Z Boban, WK Subczynski, M Raguz - Membranes, 2023 - mdpi.com
Cholesterol (Chol) is an essential component of animal cell membranes and is most
abundant in plasma membranes (PMs) where its concentration typically ranges from 10 to …

The Interaction between Amyloid-β Peptides and Anionic Lipid Membranes Containing Cholesterol and Melatonin

H Dies, L Toppozini, MC Rheinstädter - PLoS One, 2014 - journals.plos.org
One of the hallmarks of Alzheimer's disease is the formation of senile plaques, primarily
consisting of amyloid-(A) peptides. Peptide-membrane and peptide-lipid interactions are …

Liposomes came first: The early history of liposomology

V Weissig - Liposomes: Methods and Protocols, 2017 - Springer
It has been a long journey from Pliny the Elder (23–79 AD) to the FDA approval of the first
injectable Nanomedicine in 1997. It has been a journey powered by intellectual curiosity …

Formation of cholesterol-rich supported membranes using solvent-assisted lipid self-assembly

SR Tabaei, JA Jackman, SO Kim, B Liedberg, W Knoll… - Langmuir, 2014 - ACS Publications
This paper describes the application of a solvent-exchange method to prepare supported
membranes containing high fractions of cholesterol (up to∼ 57 mol%) in an apparent …

Functions of cholesterol and the cholesterol bilayer domain specific to the fiber-cell plasma membrane of the eye lens

WK Subczynski, M Raguz, J Widomska… - The Journal of …, 2012 - Springer
The most unique feature of the eye lens fiber-cell plasma membrane is its extremely high
cholesterol content. Cholesterol saturates the bulk phospholipid bilayer and induces …

Mechanical properties of the high cholesterol-containing membrane: An AFM study

NK Khadka, R Timsina, E Rowe, M O'Dell… - Biochimica et Biophysica …, 2021 - Elsevier
Cholesterol (Chol) content in most cellular membranes does not exceed 50 mol%, only in
the eye lens's fiber cell plasma membrane, its content surpasses 50 mol%. At this high …

Using spin-label electron paramagnetic resonance (EPR) to discriminate and characterize the cholesterol bilayer domain

M Raguz, L Mainali, J Widomska… - Chemistry and physics of …, 2011 - Elsevier
Electron paramagnetic resonance (EPR) spin-labeling methods make it possible not only to
discriminate the cholesterol bilayer domain (CBD) but also to obtain information about the …

Properties of membranes derived from the total lipids extracted from the human lens cortex and nucleus

L Mainali, M Raguz, WJ O'Brien, WK Subczynski - Biophysical Journal, 2013 - cell.com
The organization and physical properties of lens lipid membranes made from the total lipids
extracted from the human lens cortex and nucleus of 41-to 60-year-old donors were …