BACKGROUND: In August 2010 reports of a possible association between exposure to
AS03 adjuvanted pandemic A (H1N1) pdm09 vaccine and occurrence of narcolepsy in …

Purpose In this proof‐of‐concept paper we describe the framework, process, and
preliminary results of combining data from European electronic healthcare record (EHR) …

Background Use of selective COX-2 non-steroidal anti-inflammatory drugs (NSAIDs)(coxibs)
has been associated with an increased risk of acute myocardial infarction (AMI). However …

Background and purpose A multi-country European study using data from six healthcare
databases from four countries was performed to evaluate in a large study population (> 32 …

Objective Data from electronic healthcare records (EHR) can be used to monitor drug safety,
but in order to compare and pool data from different EHR databases, the extraction of …

Purpose To provide estimates of the number and types of drugs that can be monitored for
safety surveillance using electronic healthcare databases. Methods Using data from eight …

Abstract Introduction Electronic healthcare databases (EHDs) are used increasingly for post-
marketing drug safety surveillance and pharmacoepidemiology in Europe and North …

Conclusion: Using our conceptual framework we found several areas that would benefit from
research to identify optimal standards for production of empirical knowledge from existing …

Background We are currently facing a proliferation of heterogeneous biomedical data
sources accessible through various knowledge-based applications. These data are …

Purpose Pharmacovigilance methods have advanced greatly during the last decades,
making post‐market drug assessment an essential drug evaluation component. These …