Rationale The biopsychosocial (BPS) model that challenged the historically dominant
biomedical model remains influential today. This model considers biological, psychological …

Inactivated and live attenuated vaccines have improved human life and significantly reduced
morbidity and mortality of several human infectious diseases. However, these vaccines have …

Mycobacterium tuberculosis (Mtb) is one of the most life-threatening mycobacterial species
which is increasing the death rate due to emerging multi-drug resistant (MDR) strains …

The development of a vaccine against tuberculosis (TB), a disease caused by
Mycobacterium tuberculosis, is urgently needed. The only currently available vaccine, M …

Despite some major progress made in developing tuberculosis (TB) vaccine strategies, with
a dozen novel vaccines currently in the clinical pipeline, the world is still missing an effective …

The global burden of tuberculosis (TB) is aggravated by the continuously increasing
emergence of drug resistance, highlighting the need for innovative therapeutic options. The …

The World Health Organization identifies tuberculosis (TB), caused by Mycobacterium
tuberculosis, as a leading infectious killer. Although conventional treatments for TB exist …

Background Increasing evidence supports that antibodies can protect against active
tuberculosis (TB) but knowledge of potentially protective antigens, especially in the airways …

Objectives To identify new potential host biomarkers in blood to discriminate between active
TB patients, uninfected (NoTBI) and latently infected contacts (LTBI). Methods A blood cell …

Introduction: More than two billion people are latently infected with Mycobacterium
tuberculosis. Most tuberculosis (TB)-subunit vaccines currently in various stages of clinical …