Among the chaperones and co-chaperones regulating the glucocorticoid receptor (GR),
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …

The general objective of the review is to explain the interaction between HIF-1 and
mitochondria. On the one hand, this review describes the effects of HIF-1 on mitochondrial …

Lipid droplets (LDs) are organelles that compartmentalize nonbilayer-forming lipids in the
aqueous cytoplasm of cells. They are ubiquitous in most organisms, including in animals …

Class III histone deacetylases (HDACs) belong to the proteasome family, comprising seven
family members identified in mammalian cells, identified Sirt1–Sirt7. As an important …

Cytoplasmic lipid droplets (LDs) can store neutral lipids as an energy source when needed
and also regulate the key metabolic processes of intracellular lipid accumulation, which is …

Enhancer of zeste homolog 2 (EZH2), a methyltransferase that di-and tri-methylates lysine-
27 of histone H3, largely functions as a transcriptional repressor, and plays a critical role in …

Initially described as lytic bodies due to their degradative and recycling functions, lysosomes
play a critical role in metabolic adaptation to nutrient availability. More recently, the …

Autophagy is crucial for maintaining cellular homeostasis, and can be activated after
ischemic stroke. It also participates in nerve injury and repair. The purpose of this study was …

The COVID-19 pandemic, caused by the coronavirus, SARS-CoV-2, has claimed millions of
lives worldwide in the past two years. Fatalities among the elderly with underlying …

VPS34 is well-known to be the unique member of the class III phosphoinositide 3-kinase
(PI3K) family, forming VPS34 complex 1 and complex 2, which are involved in several key …