C–H bond activation and decarboxylation are two significant processes in organic synthesis.
The combination of these processes provides a novel synthetic strategy, that is …

Conspectus C–C single bonds are ubiquitous in organic compounds. The activation and
subsequent functionalization of C–C single bonds provide a unique opportunity to …

The extraordinary impact of metal-based complexes on synthetic methods is still recognized
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …

Carboxylic acids have gained more and more importance as versatile and renewable
starting materials for the formation of platform molecules or high-value chemicals. Many …

The last decades have seen a tremendous expanse in the application of C H activation of
many different substrate classes, including the invaluable indole scaffold. Following the …

This critical review examines transition metal-catalyzed decarboxylative couplings that have
emerged within recent years as a powerful strategy to form carbon–carbon or carbon …

Despite significant progress in aliphatic decarboxylation, an efficient and general protocol
for radical aromatic decarboxylation has lagged far behind. Herein, we describe a general …

Heteroarenes containing oxygen, nitrogen, and/or sulfur are important in numerous aspects
of chemistry and everyday life. C–H functionalization of heteroarenes represents the fastest …

This tutorial review provides a comparison between the concepts of catalytic decarboxylative
and decarbonylative couplings for the ipso-substitution of carboxylate groups, and illustrates …

Over the last two decades, transition-metal catalyzed C–H functionalization of indoles has
emerged as an area of extensive research and tremendous progress has been made in this …