Age-associated B cells in autoimmune diseases
IC Mouat, E Goldberg, MS Horwitz - Cellular and Molecular Life Sciences, 2022 - Springer
Age-associated B cells (ABCs) are a transcriptionally and functionally unique B cell
population. In addition to arising with age and following infection, ABCs are expanded …
population. In addition to arising with age and following infection, ABCs are expanded …
CXCR3 in T cell function
JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
CXCR3 ligands: redundant, collaborative and antagonistic functions
JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
CXCR3 ligands in disease and therapy
K Van Raemdonck, PE Van den Steen… - Cytokine & growth factor …, 2015 - Elsevier
Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …
IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
JH Dufour, M Dziejman, MT Liu, JH Leung… - The Journal of …, 2002 - journals.aai.org
Abstract IFN-γ-inducible protein 10 (IP-10, CXCL10), a chemokine secreted from cells
stimulated with type I and II IFNs and LPS, is a chemoattractant for activated T cells …
stimulated with type I and II IFNs and LPS, is a chemoattractant for activated T cells …
CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
Signals from the microenvironment have a profound influence on the maintenance and/or
progression of hematopoietic and epithelial cancers. Mesenchymal or marrow-derived …
progression of hematopoietic and epithelial cancers. Mesenchymal or marrow-derived …
The emerging role of CXCL10 in cancer
The chemokine interferon-γ inducible protein 10 kDa (CXCL10) is a member of the CXC
chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 …
chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 …
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1
A subset of blood cells from patients with B-cell chronic lymphocytic leukemia (CLL)
spontaneously differentiates in vitro into large, round, or fibroblast-like adherent cells that …
spontaneously differentiates in vitro into large, round, or fibroblast-like adherent cells that …
Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells
HJ Hwang, YR Lee, D Kang, HC Lee, HR Seo, JK Ryu… - Cancer letters, 2020 - Elsevier
The effects of senescence associated secretory phenotype (SASP) from therapy-induced
senescent endothelial cells on tumor microenvironment (TME) remains to be clarified. Here …
senescent endothelial cells on tumor microenvironment (TME) remains to be clarified. Here …
The chemokine system in cancer biology and therapy
A Mantovani, B Savino, M Locati, L Zammataro… - Cytokine & growth factor …, 2010 - Elsevier
Chemokines are a key component of cancer-related inflammation. Chemokines and
chemokine receptors are downstream of genetic events that cause neoplastic transformation …
chemokine receptors are downstream of genetic events that cause neoplastic transformation …