Vascular mechanotransduction
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
Cannabinoid ligands targeting TRP channels
Transient receptor potential (TRP) channels are a group of membrane proteins involved in
the transduction of a plethora of chemical and physical stimuli. These channels modulate ion …
the transduction of a plethora of chemical and physical stimuli. These channels modulate ion …
[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
Ion channels in cancer: are cancer hallmarks oncochannelopathies?
N Prevarskaya, R Skryma, Y Shuba - Physiological reviews, 2018 - journals.physiology.org
Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …
all cancer cell genotypes generally translate into several common pathophysiological …
[PDF][PDF] Chlorella and spirulina microalgae as sources of functional foods
LM Andrade, CJ Andrade, M Dias… - Nutraceuticals, and …, 2018 - researchgate.net
Chlorella and Spirulina are the two of the most well-known microalgae genus. Both
microalgae genus have a significant content of proteins, vitamins, pigments, fatty acids …
microalgae genus have a significant content of proteins, vitamins, pigments, fatty acids …
[HTML][HTML] Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
NR Tykocki, EM Boerman… - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress
SM Swain, RA Liddle - Journal of Biological Chemistry, 2021 - ASBMB
The ion channels Piezo1 and TRPV4 have both, independently, been implicated in high
venous pressure–and fluid shear stress–induced vascular hyperpermeability in endothelial …
venous pressure–and fluid shear stress–induced vascular hyperpermeability in endothelial …
TRPV4: molecular conductor of a diverse orchestra
Transient receptor potential vanilloid type 4 (TRPV4) is a calcium-permeable nonselective
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease
MS Steinhoff, B von Mentzer, P Geppetti… - Physiological …, 2014 - journals.physiology.org
The tachykinins, exemplified by substance P, are one of the most intensively studied
neuropeptide families. They comprise a series of structurally related peptides that derive …
neuropeptide families. They comprise a series of structurally related peptides that derive …