Circuit mechanisms of Parkinson's disease

MM McGregor, AB Nelson - Neuron, 2019 - cell.com
Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

Fractionating impulsivity: neuropsychiatric implications

JW Dalley, TW Robbins - Nature Reviews Neuroscience, 2017 - nature.com
The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

MF Bastide, WG Meissner, B Picconi, S Fasano… - Progress in …, 2015 - Elsevier
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients

D Weintraub, J Koester, MN Potenza… - Archives of …, 2010 - jamanetwork.com
Context An association between dopamine-replacement therapies and impulse control
disorders (ICDs) in Parkinson disease (PD) has been suggested in preliminary studies …

Clinical spectrum of impulse control disorders in Parkinson's disease

D Weintraub, AS David, AH Evans, JE Grant… - Movement …, 2015 - Wiley Online Library
Impulse control disorders (ICDs), including compulsive gambling, buying, sexual behavior,
and eating, are a serious and increasingly recognized psychiatric complication in …

Validation of the questionnaire for impulsive‐compulsive disorders in Parkinson's disease

D Weintraub, S Hoops, JA Shea… - … : official journal of the …, 2009 - Wiley Online Library
As no comprehensive assessment instrument for impulse control disorders (ICDs) in
Parkinson's disease (PD) exists, the aim of this study was to design and assess the …

Parkinson's disease: the quintessential neuropsychiatric disorder

D Weintraub, DJ Burn - Movement Disorders, 2011 - Wiley Online Library
Although diagnosed by characteristic motor features, Parkinson's disease may be preceded,
and is frequently accompanied by, a wide range of cognitive and neuropsychiatric features …

Questionnaire for impulsive‐compulsive disorders in Parkinson's Disease–Rating Scale

D Weintraub, E Mamikonyan, K Papay… - Movement …, 2012 - Wiley Online Library
Impulse control disorders and related disorders (hobbyism‐punding and dopamine
dysregulation syndrome) occur in 15% to 20% of Parkinson's disease (PD) patients. We …

Association of dopamine agonist use with impulse control disorders in Parkinson disease

D Weintraub, AD Siderowf, MN Potenza… - Archives of …, 2006 - jamanetwork.com
Objective To determine the frequency and correlates of impulse control disorders (ICDs) in
Parkinson disease (PD). Design An unstructured screening interview for ICDs (compulsive …

Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study

PJ Garcia-Ruiz, JCM Castrillo… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background Impulse control disorders (ICDs) encompass a wide spectrum of abnormal
behaviour frequently found in cases of Parkinson's disease (PD) treated with dopamine …