Obesity has become a global epidemic that has a negative impact on population health and
the economy of nations. Genetic predispositions have been demonstrated to have a …

Pioneering studies performed over the past few decades demonstrate links between
epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most …

Background: Exercise therapy plays an important role in the prevention and treatment of
type 2 diabetes (T2DM). The mechanism of exercise therapy in the improvement of …

Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …

Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …

Epigenetic changes are caused by biochemical regulators of gene expression that can be
transferred across generations or through cell division. Epigenetic modifications can arise …

Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …

Aim: DNA methylation programs gene expression and is involved in numerous biological
processes. Accumulating evidence supports transgenerational inheritance of DNA …