Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy

J Han, J Lim, CPJ Wang, JH Han, HE Shin, SN Kim… - Nano …, 2023 - Springer
Cancer immunotherapy, which harnesses the power of the immune system, has shown
immense promise in the fight against malignancies. Messenger RNA (mRNA) stands as a …

Stimuli-responsive nanoassemblies for targeted delivery against tumor and its microenvironment

CS Sia, HP Lim, BT Tey, BH Goh, LE Low - Biochimica et Biophysica Acta …, 2022 - Elsevier
Despite the emergence of various cancer treatments, such as surgery, chemotherapy,
radiotherapy, and immunotherapy, their use remains restricted owing to their limited tumor …

Senescent cancer cell-derived nanovesicle as a personalized therapeutic cancer vaccine

J Hong, M Jung, C Kim, M Kang, S Go… - … & Molecular Medicine, 2023 - nature.com
The development of therapeutic cancer vaccines (TCVs) that provide clinical benefits is
challenging mainly due to difficulties in identifying immunogenic tumor antigens and …

Nanoparticle-based chimeric antigen receptor therapy for cancer immunotherapy

S Shin, P Lee, J Han, SN Kim, J Lim, DH Park… - Tissue Engineering and …, 2023 - Springer
Adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) has
emerged as an innovative immunotherapy for hematological cancer treatment. However, the …

Stimuli-controllable iron oxide nanoparticle assemblies: Design, manipulation and bio-applications

LE Low, HP Lim, YS Ong, SP Siva, CS Sia… - Journal of Controlled …, 2022 - Elsevier
Despite its wide establishment over the years, iron oxide nanoparticle (IONP) still draws
extensive interest in the biomedical fields due to its biocompatibility, biodegradability …

Photodynamic therapy with NIR-II probes: review on state-of-the-art tools and strategies

Y Yang, S Jiang, S Stanciu, H Peng, A Wu… - Materials Horizons, 2024 - pubs.rsc.org
In 2022 10% of the world's population was aged 65+, and by 2100 this segment is expected
to hit 25%. These demographic changes place considerable pressure over healthcare …

Advances in Nanoplatforms for Immunotherapy Applications Targeting the Tumor Microenvironment

N Zhang, J Zhou, S Li, W Cai, B Ru, J Hu… - Molecular …, 2024 - ACS Publications
Cancer immunotherapy is a treatment method that activates or enhances the autoimmune
response of the body to fight tumor growth and metastasis, has fewer toxic side effects and a …

[HTML][HTML] Immunotherapy targeting the obese white adipose tissue microenvironment: Focus on non-communicable diseases

L Priscilla, C Yoo, S Jang, S Park, G Lim, T Kim… - Bioactive Materials, 2024 - Elsevier
Obesity triggers inflammatory responses in the microenvironment of white adipose tissue,
resulting in chronic systemic inflammation and the subsequent development of non …

[HTML][HTML] Suppressing cancer by damaging cancer cell DNA using LED irradiation

YJ Kim, J Song, DH Lee, SH Um, SH Bhang - Journal of Photochemistry …, 2023 - Elsevier
Background High-energy irradiation eliminates cancer cells by destroying their genetic
components. However, there are several side effects from doing this, such as fatigue …

Recent developments in chemodrug-loaded nanomedicines and their application in combination cancer immunotherapy

N Shim, H Cho, SI Jeon, K Kim - Journal of Pharmaceutical Investigation, 2024 - Springer
Background In recent studies of cancer therapies, chemodrugs have attracted interest,
acting not only as traditional chemotherapeutic agents but also as anticancer immune …