Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Adult tissue-specific stem cells have the capacity to self-renew and generate functional
differentiated cells that replenish lost cells throughout an organism's lifetime. Studies on …

Patients preparing to undergo gonadotoxic medical therapy, radiation therapy, or
gonadectomy should be provided with prompt counseling regarding available options for …

Zika virus (ZIKV) persists in the semen of male patients, a first for flavivirus infection. Here,
we demonstrate that ZIKV can induce inflammation in the testis and epididymidis, but not in …

Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout a man's life and
may have application for treating some cases of male infertility, including those caused by …

Stem cells are rare cells that are uniquely capable of both reproducing themselves (self-
renewing) and generating the differentiated cell types that are needed to carry out …

This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

The recently developed testis cell transplantation method provides a powerful approach to
studying the biology of the male germline stem cell and its microenvironment, the stem cell …

Spermatogenesis is a productive and highly organized process that generates virtually
unlimited numbers of sperm during adulthood. Continuous proliferation and differentiation of …