[HTML][HTML] Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans

M Geva-Sagiv, EA Mankin, D Eliashiv, S Epstein… - Nature …, 2023 - nature.com
Memory consolidation during sleep is thought to depend on the coordinated interplay
between cortical slow waves, thalamocortical sleep spindles and hippocampal ripples, but …

Aperiodic sleep networks promote memory consolidation

RF Helfrich, JD Lendner, RT Knight - Trends in Cognitive Sciences, 2021 - cell.com
Hierarchical synchronization of sleep oscillations establishes communication pathways to
support memory reactivation, transfer, and consolidation. From an information-theoretical …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model

AS Cone, X Yuan, L Sun, LC Duke, MP Vreones… - Theranostics, 2021 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …

Alterations of sleep oscillations in Alzheimer's disease: a potential role for GABAergic neurons in the cortex, hippocampus, and thalamus

F Katsuki, D Gerashchenko, RE Brown - Brain research bulletin, 2022 - Elsevier
Sleep abnormalities are widely reported in patients with Alzheimer's disease (AD) and are
linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect …

[HTML][HTML] Predicting real world spatial disorientation in Alzheimer's disease patients using virtual reality navigation tests

V Puthusseryppady, S Morrissey, H Spiers, M Patel… - Scientific Reports, 2022 - nature.com
Spatial navigation impairments in Alzheimer's disease (AD) have been suggested to
underlie patients experiencing spatial disorientation. Though many studies have highlighted …

[HTML][HTML] Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice

Y Ni, Y Feng, D Shen, M Chen, X Zhu, Q Zhou… - Journal of …, 2022 - Springer
Abstract Background Anti-IgLON5 disease is a rare neurological disorder associated with
autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations …

[HTML][HTML] Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease

H Zhou, H Li, N Gowravaram, M Quan, N Kausar… - Scientific Reports, 2022 - nature.com
The Alzheimer's disease-associated peptide amyloid-beta (Aβ) has been associated with
neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or neural …

An 8-Week Administration of Bifidobacterium bifidum and Lactobacillus plantarum Combined with Exercise Training Alleviates Neurotoxicity of Aβ and Spatial …

S Shamsipour, G Sharifi, F Taghian - Journal of Molecular Neuroscience, 2021 - Springer
This study aimed to determine the effects of 8 weeks of an administration of Bifidobacterium
bifidum and Lactobacillus plantarum combined with exercise training on neurotoxicity of Aβ …

[HTML][HTML] Normal and abnormal sharp wave ripples in the hippocampal-entorhinal cortex system: implications for memory consolidation, Alzheimer's disease, and …

ZH Zhen, MR Guo, HM Li, OY Guo, JL Zhen… - Frontiers in Aging …, 2021 - frontiersin.org
The appearance of hippocampal sharp wave ripples (SWRs) is an electrophysiological
biomarker for episodic memory encoding and behavioral planning. Disturbed SWRs are …

Artificial sharp-wave-ripples to support memory and counter neurodegeneration

J Keil, H Kiiski, L Doherty, V Hernandez-Urbina… - Brain research, 2023 - Elsevier
Abstract Information processed in our sensory neocortical areas is transported to the
hippocampus during memory encoding, and between hippocampus and neocortex during …