[HTML][HTML] Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans
M Geva-Sagiv, EA Mankin, D Eliashiv, S Epstein… - Nature …, 2023 - nature.com
Memory consolidation during sleep is thought to depend on the coordinated interplay
between cortical slow waves, thalamocortical sleep spindles and hippocampal ripples, but …
between cortical slow waves, thalamocortical sleep spindles and hippocampal ripples, but …
Aperiodic sleep networks promote memory consolidation
Hierarchical synchronization of sleep oscillations establishes communication pathways to
support memory reactivation, transfer, and consolidation. From an information-theoretical …
support memory reactivation, transfer, and consolidation. From an information-theoretical …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …
than 44 million people worldwide. Despite the high disease burden, there is no effective …
Alterations of sleep oscillations in Alzheimer's disease: a potential role for GABAergic neurons in the cortex, hippocampus, and thalamus
Sleep abnormalities are widely reported in patients with Alzheimer's disease (AD) and are
linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect …
linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect …
[HTML][HTML] Predicting real world spatial disorientation in Alzheimer's disease patients using virtual reality navigation tests
V Puthusseryppady, S Morrissey, H Spiers, M Patel… - Scientific Reports, 2022 - nature.com
Spatial navigation impairments in Alzheimer's disease (AD) have been suggested to
underlie patients experiencing spatial disorientation. Though many studies have highlighted …
underlie patients experiencing spatial disorientation. Though many studies have highlighted …
[HTML][HTML] Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice
Y Ni, Y Feng, D Shen, M Chen, X Zhu, Q Zhou… - Journal of …, 2022 - Springer
Abstract Background Anti-IgLON5 disease is a rare neurological disorder associated with
autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations …
autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations …
[HTML][HTML] Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease
H Zhou, H Li, N Gowravaram, M Quan, N Kausar… - Scientific Reports, 2022 - nature.com
The Alzheimer's disease-associated peptide amyloid-beta (Aβ) has been associated with
neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or neural …
neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or neural …
An 8-Week Administration of Bifidobacterium bifidum and Lactobacillus plantarum Combined with Exercise Training Alleviates Neurotoxicity of Aβ and Spatial …
This study aimed to determine the effects of 8 weeks of an administration of Bifidobacterium
bifidum and Lactobacillus plantarum combined with exercise training on neurotoxicity of Aβ …
bifidum and Lactobacillus plantarum combined with exercise training on neurotoxicity of Aβ …
[HTML][HTML] Normal and abnormal sharp wave ripples in the hippocampal-entorhinal cortex system: implications for memory consolidation, Alzheimer's disease, and …
ZH Zhen, MR Guo, HM Li, OY Guo, JL Zhen… - Frontiers in Aging …, 2021 - frontiersin.org
The appearance of hippocampal sharp wave ripples (SWRs) is an electrophysiological
biomarker for episodic memory encoding and behavioral planning. Disturbed SWRs are …
biomarker for episodic memory encoding and behavioral planning. Disturbed SWRs are …
Artificial sharp-wave-ripples to support memory and counter neurodegeneration
Abstract Information processed in our sensory neocortical areas is transported to the
hippocampus during memory encoding, and between hippocampus and neocortex during …
hippocampus during memory encoding, and between hippocampus and neocortex during …