Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

Objective Prevalence rates of depression and anxiety in patients with Multiple Sclerosis
(MS) vary widely across studies. Aim of this systematic review and meta-analysis was to a) …

Social cognition includes a range of cognitive processes that help individuals to understand
how others think and feel. There is emerging evidence that social cognitive deficits may …

Physical activity, by definition, is any skeletal muscle body movement that results in energy
expenditure. In the last few decades, a plethora of scientific evidences have accumulated …

Diagnostic criteria for mood disorders including major depressive disorder (MDD) largely
ignore biological factors in favor of behavioral symptoms. Compounding this paucity of …

In response to a peripheral infection, innate immune cells produce pro-inflammatory
cytokines that act on the brain to cause sickness behaviour. When activation of the …

Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric
manifestations have a high prevalence in MS patients and may worsen the illness …

Background Individuals with multiple sclerosis (MS) are often plagued by the unpredictability
of their disease and have to contend with uncertainty in their life and significant life changes …

Mood disorder and depressive syndromes represent a common comorbid condition in
neurological disorders with a prevalence rate that ranges between 20% and 50% of patients …

Objective: Health-related quality of life (HRQOL) is often much reduced among individuals
with multiple sclerosis (MS), and incidences of depression, fatigue, and anxiety are high. We …