Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for 57% of
cases of liver cirrhosis and 78% of cases of primary liver cancer worldwide and cause a …

Hepatitis C (HCV) is a major cause of liver disease, in which a third of individuals with
chronic HCV infections may develop liver cirrhosis. In a chronic HCV infection, host immune …

Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and
liver disease. The characterization of viral populations that successfully initiate infection, and …

There are 257 million persons worldwide with chronic hepatitis B virus (HBV) infection, a
leading causes of liver cancer. Almost all adults with acute HBV infection have a rapid …

Despite major advances in the understanding and treatment of hepatitis C, a preventive
vaccine remains elusive. The marked genetic diversity and multiple mechanisms of …

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, cirrhosis, and
death; it is estimated that 180 million persons are infected with HCV worldwide. The …

Effective innate and adaptive immune responses are essential for the control of hepatitis C
virus (HCV) infection. Indeed, elimination of HCV during acute infection correlates with an …

Over recent years, it has become increasingly accepted that virus-specific CD4+ and CD8+
T cell responses play a major role in outcome and pathogenesis of hepatitis C virus (HCV) …

BACKGROUND & AIMS: HLA class I alleles are linked to spontaneous control of hepatitis C
virus (HCV) and human immunodeficiency virus− 1, but for HCV the roles of particular …

The efficacy of specifically targeted anti‐viral therapy for hepatitis C virus (HCV)(STAT‐C),
including HCV protease and polymerase inhibitors, is limited by the presence of drug …