The [2+ 2] photocycloaddition is undisputedly the most important and most frequently used
photochemical reaction. In this review, it is attempted to cover all recent aspects of [2+ 2] …

Sizable resources, both financial and human, are invested each year in the development of
new pharmaceutical agents. However, despite improved techniques, the new compounds …

Covering: 2000 to 2015 Molecules containing vicinal all-carbon quaternary stereocenters
are found in many secondary metabolites, and they exhibit a variety of biological and …

Enantioselective reactions catalyzed by small organic molecules (asymmetric
organocatalysis) have emerged as one of the most elegant cutting-edge strategies of …

Terpenoids are a very prominent class of natural compounds produced in diverse genera of
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …

This review describes the additions of allylmagnesium reagents to carbonyl compounds and
to imines, focusing on the differences in reactivity between allylmagnesium halides and …

The Illicium sesquiterpenes are a family of natural products containing over 100 highly
oxidized and structurally complex members, many of which display interesting biological …

Neurodegenerative diseases and spinal cord injury affect approximately 50 million people
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …

Saturated oxygen heterocycles are widely found in a broad array of natural products and
other biologically active molecules. In medicinal chemistry, small and medium rings are also …

We report an asymmetric, catalytic transannular aldolization that provides polycyclic
products useful for natural product synthesis. We found that a proline-derivative catalyzes …