Plant voltage-gated K+ channels have been referred to as “plant Shakers” in reference to
animal Shaker channels, the first K+ channels identified. Recent advances in our knowledge …

Fertilization is exceptionally complex and, depending on the species, happens in entirely
different environments. External fertilizers in aquatic habitats, like marine invertebrates or …

Ether-a-go-go (EAG) channels are key regulators of neuronal excitability and tumorigenesis.
EAG channels contain an N-terminal Per-Arnt-Sim (PAS) domain that can regulate currents …

Background and Purpose Natural flavonoids are ubiquitous in dietary plants and vegetables
and have been proposed to have antiviral, antioxidant, cardiovascular protective and …

The human ether-à-go-go–related gene (hERG) encodes a K+ channel crucial for
repolarization of the cardiac action potential. EAG-related gene (ERG) channels contain a C …

Despite sharing a common architecture with archetypal voltage-gated ion channels (VGICs),
hyperpolarization-and cAMP-activated ion (HCN) channels open upon hyperpolarization …

Calcium in the flagellum controls sperm navigation. In sperm of marine invertebrates and
mammals, Ca2+ signalling has been intensely studied, whereas for fish little is known. In …

To preserve ionic homeostasis (primarily Ca2+, K+, Na+, and Cl−), in the airway smooth
muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx …

KCNH channels are expressed across a vast phylogenetic and evolutionary spectrum. In
humans, they function in a wide range of tissues and serve as biomarkers and targets for …

Abstract Eag1 (ether-à-go-go-1), a member of the voltage-dependent potassium channel
family, is expressed mainly in the brain, and at low levels in placenta, testis, and adrenal …