The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

Female gut and genital tract microbiota-induced crosstalk and differential effects of short-chain fatty acids on immune sequelae

E Amabebe, DOC Anumba - Frontiers in Immunology, 2020 - frontiersin.org
The gut and genital tract microbiota of females represent very complex biological
ecosystems that are in continuous communication with each other. The crosstalk between …

The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions

A Mitra, DA MacIntyre, G Ntritsos, A Smith… - Nature …, 2020 - nature.com
Emerging evidence suggests associations between the vaginal microbiota (VMB)
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …

Host–vaginal microbiota interactions in the pathogenesis of bacterial vaginosis

CA Muzny, P Łaniewski, JR Schwebke… - Current opinion in …, 2020 - journals.lww.com
Elucidating the cause of bacterial vaginosis has important implications for diagnosis and
treatment. Our current bacterial vaginosis pathogenesis model provides a framework for key …

Changes of the vaginal microbiota in HPV infection and cervical intraepithelial neoplasia: a cross-sectional analysis

W Lin, Q Zhang, Y Chen, B Dong, H Xue, H Lei, Y Lu… - Scientific reports, 2022 - nature.com
This study aimed to explore the changes of the vaginal microbiota and enzymes in the
women with high-risk human papillomavirus (HR-HPV) infection and cervical lesions. A total …

Human papillomavirus infection and cervical intraepithelial neoplasia progression are associated with increased vaginal microbiome diversity in a Chinese cohort

Y Chen, X Qiu, W Wang, D Li, A Wu, Z Hong, W Di… - BMC infectious …, 2020 - Springer
Background In this study, the association between human papillomavirus (HPV) infection
and related cervical intraepithelial neoplasia (CIN) or cervical cancer and vaginal …

The female reproductive tract microbiotas, inflammation, and gynecological conditions

M Gholiof, E Adamson-De Luca… - Frontiers in Reproductive …, 2022 - frontiersin.org
The intricate interactions between the host cells, bacteria, and immune components that
reside in the female reproductive tract (FRT) are essential in maintaining reproductive tract …

The role of HPV‑induced epigenetic changes in cervical carcinogenesis

MLR Da Silva, BHDR De Albuquerque… - Biomedical …, 2021 - spandidos-publications.com
Cervical cancer is associated with infection by certain types of human papillomaviruses
(HPVs), and this affects women worldwide. Despite the improvements in prevention and …

The vaginal metabolome and microbiota of cervical HPV‐positive and HPV‐negative women: a cross‐sectional analysis

JC Borgogna, MD Shardell, EK Santori… - … Journal of Obstetrics …, 2020 - Wiley Online Library
Objective Characterise the vaginal metabolome of cervical HPV‐infected and uninfected
women. Design Cross‐sectional. Setting The Center for Health Behavior Research at the …

[HTML][HTML] The role of gut microbiome in cancer genesis and cancer prevention

N Akbar, NA Khan, JS Muhammad, R Siddiqui - Health Sciences Review, 2022 - Elsevier
Cancer is the second leading cause of fatalities at the global level, and the involvement of
microbes in several diseases, including cancer is well known. The gut microbiome is known …