Pancreatic cancer is a devastating gastrointestinal cancer characterized by late diagnosis,
limited treatment success and dismal prognosis. Exocrine tumours account for 95% of …

Anchorage-independent survival of cancer cells is associated with metastasis as it enables
cells to travel to secondary target sites. Tissue integrity is generally maintained by …

Abstract G-quadruplexes (G4) are secondary four-stranded DNA helical structures
consisting of guanine-rich nucleic acids, which can be formed in the promoter regions of …

More than 30,000 people develop pancreatic adeno-carcinoma each year in the United
States, and almost all are expected to die from the disease. 1 The 5-year survival rate is 5 …

Pancreatic cancer is one of the most lethal tumours of the gastrointestinal tract. The ability to
predict which patients would benefit most from surgical intervention and/or chemotherapy …

In this manuscript we describe the preparation of an oxygen-loaded microbubble (O 2 MB)
platform for the targeted treatment of pancreatic cancer using both sonodynamic therapy …

We report here that a tetra-substituted naphthalene-diimide derivative (MM41) has
significant in vivo anti-tumour activity against the MIA PaCa-2 pancreatic cancer xenograft …

Pancreatic adenocarcinoma is characterized by poor prognosis, because of late diagnosis
and lack of response to chemo-and/or radiation therapies. Resistance to apoptosis mainly …

Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients
suffering from this disorder experience dramatic mood swings with a wide variety of typical …

Background This study investigates sex disparities in clinical outcomes and tumour immune
profiles in patients with pancreatic ductal adenocarcinoma (PDAC) who underwent upfront …