Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetes mellitus

S Treviño, A Díaz, E Sánchez-Lara… - Biological trace element …, 2019 - Springer
Vanadium compounds have been primarily investigated as potential therapeutic agents for
the treatment of various major health issues, including cancer, atherosclerosis, and …

Vanadium compounds in medicine

JC Pessoa, S Etcheverry, D Gambino - Coordination chemistry reviews, 2015 - Elsevier
Vanadium is a transition metal that, being ubiquitously distributed in soil, crude oil, water
and air, also found roles in biological systems and is an essential element in most living …

Radiation resistance: a matter of transcription factors

C Galeaz, C Totis, A Bisio - Frontiers in oncology, 2021 - frontiersin.org
Currently, radiation therapy is one of the standard therapies for cancer treatment. Since the
first applications, the field of radiotherapy has constantly improved, both in imaging …

Parthenolide as cooperating agent for anti-cancer treatment of various malignancies

M Sztiller-Sikorska, M Czyz - Pharmaceuticals, 2020 - mdpi.com
Primary and acquired resistance of cancer to therapy is often associated with activation of
nuclear factor kappa B (NF-κB). Parthenolide (PN) has been shown to inhibit NF-κB …

Binding of vanadium ions and complexes to proteins and enzymes in aqueous solution

JC Pessoa, MFA Santos, I Correia, D Sanna… - Coordination Chemistry …, 2021 - Elsevier
The understanding of the role of vanadium enzymes and of vanadium compounds (VCs) in
biology, as well as the design of new vanadium-based species for catalysis, materials …

Betulinic acid: recent advances in chemical modifications, effective delivery, and molecular mechanisms of a promising anticancer therapy

M Ali‐Seyed, I Jantan, K Vijayaraghavan… - Chemical biology & …, 2016 - Wiley Online Library
An important method of drug discovery is examination of diverse life forms, including
medicinal plants and natural products or bioactive compounds isolated from these sources …

[PDF][PDF] Biochemical and medical importance of vanadium compounds

J Korbecki, I Baranowska-Bosiacka… - Acta Biochimica …, 2012 - frontierspartnerships.org
Vanadium belongs to the group of transition metals and is present in the air and soil
contaminants in large urban agglomerations due to combustion of fossil fuels. It forms …

Betulinic acid and its derivatives: A patent review (2008–2013)

R Csuk - Expert opinion on therapeutic patents, 2014 - Taylor & Francis
Introduction: Betulinic acid (BA) is a triterpenoid that can be obtained from renewable
resources. BA is cytotoxic to many human tumor cell lines mainly by apoptosis but cell death …

Neuropilin-1-targeted gold nanoparticles enhance therapeutic efficacy of platinum (IV) drug for prostate cancer treatment

A Kumar, S Huo, X Zhang, J Liu, A Tan, S Li, S Jin… - ACS …, 2014 - ACS Publications
Platinum-based anticancer drugs such as cisplatin, oxaliplatin, and carboplatin are some of
the most potent chemotherapeutic agents but have limited applications due to severe dose …

Additive interactions between betulinic acid and two taxanes in in vitro tests against four human malignant melanoma cell lines

P Wróblewska-Łuczka, J Cabaj, W Bąk… - International Journal of …, 2022 - mdpi.com
The incidence of melanoma is steadily increasing worldwide. Melanoma is the most lethal
skin cancer, and new therapeutic methods are being sought. Our research aimed to …