BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Importance Mendelian randomization (MR) is a statistical approach that has become
increasingly popular in the field of cardiovascular disease research. It offers a way to infer …

Mendelian randomization (MR) is a powerful tool for causal inference with observational
genome-wide association study (GWAS) summary data. Compared to the more commonly …

Background: Lipoprotein-related traits have been consistently identified as risk factors for
atherosclerotic cardiovascular disease, largely on the basis of studies of coronary artery …

Background We investigated the causal associations between the genetic liability to
cardiovascular and lifestyle risk factors and peripheral artery disease (PAD), using a …

Background Mental disorders are among the top causes of disease burden worldwide.
Existing evidence regarding the repurposing of antihypertensives for mental disorders …

Several studies have shown that women and racial and ethnic minority patients are at
increased risk of developing lower extremity peripheral artery disease and suffering adverse …

Aims/hypothesis Diabetes and hyperlipidaemia are common comorbidities in people with
hypertension. Despite similar protective effects on CVD, different classes of antihypertensive …

Classical risk factors play a major role in the initiation and development of atherosclerosis.
However, the estimation of risk for cardiovascular events based only on risk factors is often …