Biomolecular condensates are membraneless intracellular assemblies that often form via
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …

Nucleation of new peptide and protein aggregates on the surfaces of amyloid fibrils of the
same peptide or protein has emerged in the past two decades as a major pathway for both …

The aggregation of a polypeptide chain into amyloid fibrils and their accumulation and
deposition into insoluble plaques and intracellular inclusions is the hallmark of several …

The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

The spontaneous assembly of proteins into amyloid fibrils is a phenomenon central to many
increasingly common and currently incurable human disorders, including Alzheimer's and …

In this article, we consider the role of heterogeneous nucleation in β‐amyloid aggregation.
Heterogeneous nucleation is more common and occurs at lower levels of supersaturation …

Protein misfolding and aggregation have attracted immense research interests due to their
connection with an array of degenerative diseases including neurodegenerative disorders …

The β-sheet–rich amyloid core is the defining feature of protein aggregates associated with
neurodegenerative disorders. Recent investigations have revealed that there exist multiple …

Molecular architectonics has its essence in custom design and engineering of molecular
assemblies by judicious exploitation of the noncovalent forces to construct ordered …

Amyloid Diseases involve the growth of disease specific proteins into amyloid fibrils and
their deposition in protein plaques. Amyloid fibril formation is typically preceded by …