[HTML][HTML] Rise of the natural red pigment 'prodigiosin'as an immunomodulator in cancer
Cancer is a heterogeneous disease with multifaceted drug resistance mechanisms (eg,
tumour microenvironment [TME], tumour heterogeneity, and immune evasion). Natural …
tumour microenvironment [TME], tumour heterogeneity, and immune evasion). Natural …
MUTYH-associated tumor syndrome: The other face of MAP
L Magrin, D Fanale, C Brando, LR Corsini, U Randazzo… - Oncogene, 2022 - nature.com
MUTYH gene is involved in the base excision repair (BER) mechanism and its pathogenic
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
[HTML][HTML] Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
Y Ferreyra, G Rosas, AM Cock-Rada, J Araujo… - Frontiers in …, 2023 - frontiersin.org
Background There is an increasing amount of data from Latin America on the
characterization of BRCA variants; however, there is limited information from Peru. We …
characterization of BRCA variants; however, there is limited information from Peru. We …
[HTML][HTML] Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus
This study aimed to identify BRCA1/2 mutational patterns in the tissue and blood of Egyptian
colorectal cancer (CRC) patients and to study the possible correlation of this mutational …
colorectal cancer (CRC) patients and to study the possible correlation of this mutational …
[HTML][HTML] Hereditary Breast Cancer in the Brazilian State of Ceará (The CHANCE Cohort): higher-than-expected prevalence of recurrent germline pathogenic variants
ACLVC Gifoni, MAC Gifoni, CM Wotroba… - Frontiers in …, 2022 - frontiersin.org
Purpose There is a significant lack of epidemiological data on hereditary cancer in Northeast
Brazil. This is the largest study on the prevalence and mutational spectrum of cancer …
Brazil. This is the largest study on the prevalence and mutational spectrum of cancer …
[HTML][HTML] Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
E Zavaleta, N Solis, MI Palacios, LE Zevallos-Escobar… - Cancers, 2022 - mdpi.com
Simple Summary Genetic testing should be accessible to all individuals independently of
where they live. There is an unbalanced distribution of resources and health care facilities in …
where they live. There is an unbalanced distribution of resources and health care facilities in …
Worldwide CDH1 Germline Mutation Frequency
Abstract E-cadherin (CDH1 gene) germline mutations are associated with the development
of the autosomal cancer syndrome known as hereditary diffuse gastric cancer. Different …
of the autosomal cancer syndrome known as hereditary diffuse gastric cancer. Different …