The endocannabinoid system and the brain
R Mechoulam, LA Parker - Annual review of psychology, 2013 - annualreviews.org
The psychoactive constituent in cannabis, Δ9-tetrahydrocannabinol (THC), was isolated in
the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous …
the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous …
Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies
Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …
indices of drug use, including addiction severity and treatment success. However, little is …
Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings
Background The growing concern about cannabis use, the most commonly used illicit drug
worldwide, has led to a significant increase in the number of human studies using …
worldwide, has led to a significant increase in the number of human studies using …
Food and drug cues activate similar brain regions: a meta-analysis of functional MRI studies
In healthy individuals, food cues can trigger hunger and feeding behavior. Likewise,
smoking cues can trigger craving and relapse in smokers. Brain imaging studies report that …
smoking cues can trigger craving and relapse in smokers. Brain imaging studies report that …
Long-term effects of marijuana use on the brain
Questions surrounding the effects of chronic marijuana use on brain structure continue to
increase. To date, however, findings remain inconclusive. In this comprehensive study that …
increase. To date, however, findings remain inconclusive. In this comprehensive study that …
Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings
This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …
Interoception and drug addiction
MP Paulus, JL Stewart - Neuropharmacology, 2014 - Elsevier
The role of interoception and its neural basis with relevance to drug addiction is reviewed.
Interoception consists of the receiving, processing, and integrating body-relevant signals …
Interoception consists of the receiving, processing, and integrating body-relevant signals …
The neural basis of drug stimulus processing and craving: an activation likelihood estimation meta-analysis
BACKGROUND: The capacity of drug cues to elicit drug-seeking behavior is believed to play
a fundamental role in drug dependence; yet the neurofunctional basis of human drug cue …
a fundamental role in drug dependence; yet the neurofunctional basis of human drug cue …
The use of virtual reality in craving assessment and cue-exposure therapy in substance use disorders
A Hone-Blanchet, T Wensing… - Frontiers in human …, 2014 - frontiersin.org
Craving is recognized as an important diagnosis criterion for substance use disorders
(SUDs) and a predictive factor of relapse. Various methods to study craving exist; however …
(SUDs) and a predictive factor of relapse. Various methods to study craving exist; however …
Grey matter alterations associated with cannabis use: results of a VBM study in heavy cannabis users and healthy controls
Cannabis abuse is related to impairments in a broad range of cognitive functions. However,
studies on cannabis abuse in relation to brain structure are sparse and results are …
studies on cannabis abuse in relation to brain structure are sparse and results are …