Great strides have been made over the past decade toward comprehensive study of
metabolism. Mass spectrometry (MS) has played a central role by enabling measurement of …

Antibiotics target energy-consuming processes. As such, perturbations to bacterial metabolic
homeostasis are significant consequences of treatment. Here, we describe three postulates …

Microbial communities often undergo intricate compositional changes yet also maintain
stable coexistence of diverse species. The mechanisms underlying long-term coexistence …

Metabolic activity is intimately linked to T cell fate and function. Using high-resolution mass
spectrometry, we generated dynamic metabolome and proteome profiles of human primary …

Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …

Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

Recent advances in the field of immunometabolism support the concept that fundamental
processes in T cell biology, such as TCR-mediated activation and T helper lineage …

Metabolites are the small biological molecules involved in energy conversion and
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …

The remarkable diversity of specialized metabolites produced by plants has inspired several
decades of research and nucleated a long list of theories to guide empirical ecological …

Stress responses allow cells to adapt to changes in external conditions by activating specific
pathways. Here we investigate the dynamics of single cells that were subjected to acute …