Primary biliary cholangitis (PBC) is a chronic, cholestatic, autoimmune disease with a
variable progressive course. PBC can cause debilitating symptoms including fatigue and …

Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is a chronic,
autoimmune, and cholestatic disease ameliorating the biliary epithelial system causing …

This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …

Background Treatment guidelines recommend a stepwise approach to primary biliary
cholangitis: all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and …

OBJECTIVES: Adding fibrates improves liver biochemistries in patients with primary biliary
cholangitis (PBC) and suboptimal response to ursodeoxycholic acid (UDCA). As there are …

Cholestatic liver diseases result from gradual destruction of bile ducts, accumulation of bile
acids and self-perpetuation of the inflammatory process leading to damage to …

While bile acids are important for both digestion and signalling, hydrophobic bile acids can
be harmful, especially when in high concentrations. Mechanisms for the protection of …

Primary biliary cholangitis (PBC), formerly called primary biliary cirrhosis, is a chronic
cholestatic liver disease that progresses slowly to end-stage liver disease. The first Food …

Introduction: About one-third of primary biliary cholangitis (PBC) patients do not exhibit
complete response to ursodeoxycholic acid (UDCA). Some of these patients were reported …

Primary sclerosing cholangitis (PSC) is a rare disease of stricturing and destruction of the
biliary tree with a complex genetic and environmental etiology. Most patients have co …