Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …

Sickle cell anemia is a unique disease dominated by hemolytic anemia and vaso-occlusive
events. The latter trigger a version of ischemia/reperfusion (I/R) pathobiology that is singular …

The blood-brain barrier (BBB), which is located at the interface between the central nervous
system (CNS) and the circulatory system, is instrumental in establishing and maintaining the …

Mast cells (MCs) are abundantly distributed in the human intestinal mucosa and submucosa.
However, their roles and mechanisms in the development of colorectal cancer (CRC) are …

Sickle cell disease (SCD), considered the most common monogenic disease worldwide, is a
severe hemoglobin disorder. Although the genetic and molecular bases have long been …

Ochratoxin A (OTA) is a common fungal toxin that pollutes raw materials of aquatic feeds
(such as corn, soybean meal, and wheat). This study explored the effects of OTA through …

Peripheral surgery can lead to a systemic aseptic inflammatory response comprising several
mediators aiming at restoring tissue homeostasis. It induces inflammatory mechanisms …

Human microbiota communicates with its host by secreting signaling metabolites, enzymes,
or structural components. Its homeostasis strongly influences the modulation of human …

Pain is a major comorbidity of sickle cell disease (SCD). Patients with SCD may suffer from
both acute and chronic pain. Acute pain is caused by recurrent and unpredictable episodes …

P-selectin–deficient mice to study pathophysiology of sickle cell disease | Blood Advances |
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