Microtubule-associated proteins: structuring the cytoskeleton

S Bodakuntla, AS Jijumon, C Villablanca… - Trends in cell …, 2019 - cell.com
Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to
and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more …

AKAP signalling complexes: focal points in space and time

W Wong, JD Scott - Nature reviews Molecular cell biology, 2004 - nature.com
Multiprotein signalling networks create focal points of enzyme activity that disseminate the
intracellular action of many hormones and neurotransmitters. Accordingly, the spatio …

More than a marker: potential pathogenic functions of MAP2

RA DeGiosio, MJ Grubisha, ML MacDonald… - Frontiers in molecular …, 2022 - frontiersin.org
Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within
neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic …

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

KS KoSIK, CL Joachim… - Proceedings of the …, 1986 - National Acad Sciences
The detailed protein composition of the paired helical filaments (PHF) that accumulate in
human neurons in aging and Alzheimer disease is unknown. However, the identity of certain …

Nonoxidative glucose consumption during focal physiologic neural activity

PT Fox, ME Raichle, MA Mintun, C Dence - Science, 1988 - science.org
Brain glucose uptake, oxygen metabolism, and blood flow in humans were measured with
positron emission tomography, and a resting-state molar ratio of oxygen to glucose …

Tau protein function in living cells.

DG Drubin, MW Kirschner - The Journal of cell biology, 1986 - rupress.org
Tau protein from mammalian brain promotes microtubule polymerization in vitro and is
induced during nerve cell differentiation. However, the effects of tau or any other microtubule …

Tau protein binds to microtubules through a flexible array of distributed weak sites.

KA Butner, MW Kirschner - The Journal of cell biology, 1991 - rupress.org
Tau protein plays a role in the extension and maintenance of neuronal processes through a
direct association with microtubules. To characterize the nature of this association, we have …

The microtubule binding domain of tau protein

G Lee, RL Neve, KS Kosik - Neuron, 1989 - Elsevier
Tau protein is a microtubule-associated protein implicated in the spatial and temporal
specification of microtubules and has been found in the neurofibrillary tangles of Alzheimer's …

[HTML][HTML] Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes

P Mundel, HW Heid, TM Mundel, M Krüger… - The Journal of cell …, 1997 - ncbi.nlm.nih.gov
Synaptopodin is an actin-associated protein of differentiated podocytes that also occurs as
part of the actin cytoskeleton of postsynaptic densities (PSD) and associated dendritic …

The primary structure and heterogeneity of tau protein from mouse brain

G Lee, N Cowan, M Kirschner - Science, 1988 - science.org
Tau protein is a family of microtubule binding proteins, heterogeneous in molecular weight,
that are induced during neurite outgrowth and are found prominently in neurofibrillary …