Antimalarial drug resistance and implications for the WHO global technical strategy
MM Ippolito, KA Moser, JBB Kabuya… - Current epidemiology …, 2021 - Springer
Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …
[HTML][HTML] The molecular basis of antimalarial drug resistance in Plasmodium vivax
LE Buyon, B Elsworth, MT Duraisingh - International Journal for …, 2021 - Elsevier
Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …
responsible for the majority of cases outside of the African continent. While great progress …
Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression
Plasmodium vivax and P. falciparum, the parasites responsible for most human malaria
worldwide, exhibit striking biological differences, which have important clinical …
worldwide, exhibit striking biological differences, which have important clinical …
[HTML][HTML] Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
MU Ferreira, TN de Sousa, GW Rangel… - International Journal for …, 2021 - Elsevier
Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
The host targeting effect of chloroquine in malaria
C Coban - Current opinion in immunology, 2020 - Elsevier
Highlights•Chloroquine/hydroxychloroquine is an old anti-malarial drug belongs to 4-
aminoquinolines.•Chloroquine has additional anti-virus, anti-bacteria, anti-protozoan, anti …
aminoquinolines.•Chloroquine has additional anti-virus, anti-bacteria, anti-protozoan, anti …
Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region
Abstract The Asia–Pacific region faces formidable challenges in achieving malaria
elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites …
elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites …
Transgenic Anopheles mosquitoes expressing human PAI-1 impair malaria transmission
In mammals, the serine protease plasmin degrades extracellular proteins during blood clot
removal, tissue remodeling, and cell migration. The zymogen plasminogen is activated into …
removal, tissue remodeling, and cell migration. The zymogen plasminogen is activated into …
Novel highly-multiplexed AmpliSeq targeted assay for Plasmodium vivax genetic surveillance use cases at multiple geographical scales
JH Kattenberg, HV Nguyen, HL Nguyen… - Frontiers in Cellular …, 2022 - frontiersin.org
Although the power of genetic surveillance tools has been acknowledged widely, there is an
urgent need in malaria endemic countries for feasible and cost-effective tools to implement …
urgent need in malaria endemic countries for feasible and cost-effective tools to implement …
The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools
The changing epidemiology of Plasmodium vivax: Insights from conventional and novel
surveillance tools | PLOS Medicine Skip to main content Advertisement PLOS Medicine …
surveillance tools | PLOS Medicine Skip to main content Advertisement PLOS Medicine …
Genome-wide functional screening of drug-resistance genes in Plasmodium falciparum
S Iwanaga, R Kubota, T Nishi… - Nature …, 2022 - nature.com
The global spread of drug resistance is a major obstacle to the treatment of Plasmodium
falciparum malaria. The identification of drug-resistance genes is an essential step toward …
falciparum malaria. The identification of drug-resistance genes is an essential step toward …