[HTML][HTML] IgGκ Signal Peptide Enhances the Efficacy of an Influenza Vector Vaccine against Respiratory Syncytial Virus Infection in Mice
A Pulkina, K Vasilyev, A Muzhikyan… - International Journal of …, 2023 - mdpi.com
Intranasal vaccination using influenza vectors is a promising approach to developing
vaccines against respiratory pathogens due to the activation of the mucosa-associated …
vaccines against respiratory pathogens due to the activation of the mucosa-associated …
[HTML][HTML] Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand
Background Plasmodium vivax (P. vivax) is the dominant Plasmodium spp. causing the
disease malaria in low-transmission regions outside of Africa. These regions often feature …
disease malaria in low-transmission regions outside of Africa. These regions often feature …
[HTML][HTML] Efficient signal sequence of mRNA vaccines enhances the antigen expression to expand the immune protection against viral infection
Y Zhang, S Zhai, H Huang, S Qin, M Sun… - Journal of …, 2024 - Springer
The signal sequence played a crucial role in the efficacy of mRNA vaccines against virus
pandemic by influencing antigen translation. However, limited research had been conducted …
pandemic by influencing antigen translation. However, limited research had been conducted …
Conjugation of new DNA vaccine with polyethylenimine induces cellular immune response and tumor regression in neuroblastoma mouse model
MV Stegantseva, VA Shinkevich… - Experimental …, 2020 - exp-oncology.com.ua
Aim: To estimate immunogenicity and antitumor effect of new DNA vaccine against
neuroblastoma using tyrosine hydroxylase as an antigen and linear polyethylenimine (PEI) …
neuroblastoma using tyrosine hydroxylase as an antigen and linear polyethylenimine (PEI) …
Robust computational design and evaluation of peptide vaccines for cellular immunity with application to SARS-CoV-2
We present a combinatorial machine learning method to evaluate and optimize peptide
vaccine formulations, and we find for SARS-CoV-2 that it provides superior predicted display …
vaccine formulations, and we find for SARS-CoV-2 that it provides superior predicted display …
A multi-epitope DNA vaccine co-administered with monophosphoryl lipid A adjuvant provides protection against tick transmitted Ehrlichia ruminantium in sheep
SI Tshilwane, N Thema, HC Steyn, M Van Kleef… - Vaccine, 2019 - Elsevier
Previously, a heartwater experimental DNA vaccine provided 100% protection following
laboratory challenge with Ehrlichia ruminantium administered by needle but not against an …
laboratory challenge with Ehrlichia ruminantium administered by needle but not against an …
It is all in the delivery: How to augment the efficiency of DNA vaccination
JE Francis, PM Smooker - Advanced Vaccination Technologies for …, 2024 - Elsevier
Nucleic acid vaccines (DNA and RNA) have been the subject of investigation for more than
30 years. The recent successes of mRNA vaccines against COVID-19 disease have …
30 years. The recent successes of mRNA vaccines against COVID-19 disease have …
Development of a DNA vaccine expressing a secreted HIV-1 gp41 ectodomain that includes the membrane-proximal external region
L Melnychuk, L Ajamian, P Jean-Pierre, J Liang… - Vaccine, 2017 - Elsevier
A limited number of sites on the HIV-1 Envelope protein are vulnerable to broadly
neutralizing antibodies (bnAbs). One of these sites, the membrane proximal external region …
neutralizing antibodies (bnAbs). One of these sites, the membrane proximal external region …
[HTML][HTML] Protective immunity to dengue virus induced by DNA vaccines encoding nonstructural proteins in a lethal challenge immunocompetent mouse model
RPS Alves, R Andreata-Santos… - Frontiers in Medical …, 2020 - frontiersin.org
Dengue virus represents the main arbovirus affecting humans, but there are no effective
drugs or available worldwide licensed vaccine formulations capable of conferring full …
drugs or available worldwide licensed vaccine formulations capable of conferring full …
[PDF][PDF] The Investigation of Adjuvanted Solid Lipid Nanoparticles as a Novel DNA Vaccine Delivery System Against Helicobacter Pylori
JE Francis - 2021 - researchrepository.rmit.edu.au
Many therapeutic drugs, proteins and nucleic acids are vulnerable to degradation by
proteases and nucleases or suffer rapid clearance from the body by the reticulo-endothelial …
proteases and nucleases or suffer rapid clearance from the body by the reticulo-endothelial …