Dye‐loaded nanoemulsions: biomimetic fluorescent nanocarriers for bioimaging and nanomedicine

AS Klymchenko, F Liu, M Collot… - Advanced healthcare …, 2021 - Wiley Online Library
Lipid nanoemulsions (NEs), owing to their controllable size (20 to 500 nm), stability and
biocompatibility, are now frequently used in various fields, such as food, cosmetics …

From design to the clinic: practical guidelines for translating cardiovascular nanomedicine

I Cicha, C Chauvierre, I Texier, C Cabella… - Cardiovascular …, 2018 - academic.oup.com
Cardiovascular diseases (CVD) account for nearly half of all deaths in Europe and almost
30% of global deaths. Despite the improved clinical management, cardiovascular mortality is …

Pomegranate seed oil nanoemulsions for the prevention and treatment of neurodegenerative diseases: the case of genetic CJD

M Mizrahi, Y Friedman-Levi, L Larush, K Frid… - … , Biology and Medicine, 2014 - Elsevier
Neurodegenerative diseases generate the accumulation of specific misfolded proteins, such
as PrP Sc prions or A-beta in Alzheimer's diseases, and share common pathological …

Conventional versus stealth lipid nanoparticles: formulation and in vivo fate prediction through FRET monitoring

AL Lainé, J Gravier, M Henry, L Sancey… - Journal of Controlled …, 2014 - Elsevier
The determination of the nanocarrier fate in preclinical models is required before any
translation from laboratory to clinical trials. Modern fluorescent imaging techniques have …

Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant

O Binyamin, L Larush, K Frid, G Keller… - International Journal …, 2015 - Taylor & Francis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
is associated with demyelination, neurodegeneration, and sensitivity to oxidative stress. In …

Tailoring nanostructured lipid carriers for the delivery of protein antigens: Physicochemical properties versus immunogenicity studies

T Courant, E Bayon, HL Reynaud-Dougier, C Villiers… - Biomaterials, 2017 - Elsevier
New vaccine formulations are still highly anticipated in the near-future to face incoming
health challenges, such as emergence or reemergence of severe infectious diseases …

FRET Imaging Approaches for in Vitro and in Vivo Characterization of Synthetic Lipid Nanoparticles

J Gravier, L Sancey, S Hirsjärvi… - Molecular …, 2014 - ACS Publications
DiI and DiD, two fluorophores able to interact by FRET (Förster resonance energy transfer),
were coencapsulated in the core of lipid nanocapsules (LNCs) and nanoemulsions (LNEs) …

An MRI-based classification scheme to predict passive access of 5 to 50-nm large nanoparticles to tumors

A Karageorgis, S Dufort, L Sancey, M Henry… - Scientific reports, 2016 - nature.com
Nanoparticles are useful tools in oncology because of their capacity to passively accumulate
in tumors in particular via the enhanced permeability and retention (EPR) effect. However …

Polymethine dyes-loaded solid lipid nanoparticles (SLN) as promising photosensitizers for biomedical applications

G Chinigò, A Gonzalez-Paredes, A Gilardino… - … Acta Part A: Molecular …, 2022 - Elsevier
Polymethine dyes (PMD) have proved to be excellent candidates in the biomedical field for
potential applications in both diagnostic and therapeutic. However, PMD application in …

LipImage™ 815: novel dye-loaded lipid nanoparticles for long-term and sensitive in vivo near-infrared fluorescence imaging

A Jacquart, M Kéramidas, J Vollaire… - … of biomedical optics, 2013 - spiedigitallibrary.org
A new contrast agent, LipImage™ 815, has been designed and compared to previously
described indocyanine green (ICG)-loaded lipid nanoparticles (ICG-lipidots®). Both contrast …