Nanobodies: next generation of cancer diagnostics and therapeutics
The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …
The development of human serum albumin-based drugs and relevant fusion proteins for cancer therapy
H Tao, R Wang, W Sheng, Y Zhen - International journal of biological …, 2021 - Elsevier
Human serum albumin (HSA)-based therapeutics have attracted tremendous attention in the
development of anticancer agents. The versatile properties of HSA make HSA-based …
development of anticancer agents. The versatile properties of HSA make HSA-based …
A potent neutralizing nanobody against SARS‐CoV‐2 with inhaled delivery potential
J Gai, L Ma, G Li, M Zhu, P Qiao, X Li, H Zhang… - MedComm, 2021 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has become a serious
burden on global public health. Although therapeutic drugs against COVID‐19 have been …
burden on global public health. Although therapeutic drugs against COVID‐19 have been …
Ce-MOF@ Au-Based Electrochemical Immunosensor for Apolipoprotein A1 Detection Using Nanobody Technology
B Sun, G Li, Y Wu, J Gai, M Zhu, W Ji… - … Applied Materials & …, 2024 - ACS Publications
Apolipoprotein A1 (Apo-A1) is a well-recognized biomarker in tissues, closely associated
with cardiovascular diseases such as atherosclerosis, coronary artery disease, and heart …
with cardiovascular diseases such as atherosclerosis, coronary artery disease, and heart …
Tumour inhibitory activity on pancreatic cancer by bispecific nanobody targeting PD-L1 and CXCR4
S Hao, S Xu, L Li, Y Li, M Zhao, J Chen, S Zhu, Y Xie… - BMC cancer, 2022 - Springer
Background: Antibodies and derivative drugs targeting immune checkpoints have been
approved for the treatment of several malignancies, but there are fewer responses in …
approved for the treatment of several malignancies, but there are fewer responses in …
Emerging landscape of nanobodies and their neutralizing applications against SARS-CoV-2 virus
X Feng, H Wang - ACS Pharmacology & Translational Science, 2023 - ACS Publications
The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the
coronavirus disease 2019 (COVID-19) has significantly altered people's way of life. Despite …
coronavirus disease 2019 (COVID-19) has significantly altered people's way of life. Despite …
Advances in Metabolic Engineering of Pichia pastoris Strains as Powerful Cell Factories
Pichia pastoris is the most widely used microorganism for the production of secreted
industrial proteins and therapeutic proteins. Recently, this yeast has been repurposed as a …
industrial proteins and therapeutic proteins. Recently, this yeast has been repurposed as a …
Recent advancements in fusion protein technologies in oncotherapy: A review
Cancer is a complicated, adaptable, and heterogeneous disease caused by a wide variety
of genetic changes that might impair ability of cells to function normally. The majority of the …
of genetic changes that might impair ability of cells to function normally. The majority of the …
[HTML][HTML] Strategies for developing PD-1 inhibitors and future directions
Abstract PD-L1/PD-1 signaling pathway is unarguably the hottest target for developing
therapeutics against various types of cancers. With elucidation of crystal structure of PD …
therapeutics against various types of cancers. With elucidation of crystal structure of PD …
Emerging applications of nanobodies in cancer therapy
RM Awad, F Meeus, H Ceuppens, T Ertveldt… - International review of …, 2022 - Elsevier
Cancer is a heterogeneous disease, requiring treatment tailored to the unique phenotype of
the patient's tumor. Monoclonal antibodies (mAbs) and variants thereof have enabled …
the patient's tumor. Monoclonal antibodies (mAbs) and variants thereof have enabled …